Ernst-Moritz-Arndt-University Greifswald, Institute of Psychology, Department Health and Prevention, Greifswald, Germany.
BMC Public Health. 2010 Jul 19;10:424. doi: 10.1186/1471-2458-10-424.
The aims of the present study were to examine relations between parents' self-reported smoking behavior and infants' daily exposure to environmental tobacco smoke, as assessed by urinary cotinine-to-creatinine ratio (CCR), and to describe the CCR over seven days among infants at home.
A convenience sample of 27 households was drawn. Each household had to have at least one daily tobacco smoker and one child up to three years of age. Over a seven-day period, urine samples were obtained from the child daily. To examine relations between parents' self-reported smoking and infants' daily CCR, generalized estimating equation (GEE) analysis was used.
The data revealed that infants from households with indoor smoking had higher CCRs than infants in households with outdoor smoking. CCRs were higher in girls than in boys. Older infants had lower CCRs than younger infants. Smoking outside the home versus inside the home, infant's gender, and infants' age accounted for 68% of the variance in CCR in a GEE data analysis model. No increase or decrease of CCR over time was found.
The findings suggest that parents' self-reported smoking indoors at home versus outdoors is predictive of CCR among infants three and younger. Higher CCR concentrations in girls' urine need further examination. Furthermore, significant fluctuations in daily CCR were not apparent in infants over a seven-day time period.
本研究旨在探讨父母自我报告的吸烟行为与通过尿中可替宁/肌酐比值(CCR)评估的婴儿日常环境烟草烟雾暴露之间的关系,并描述家中婴儿七天内的 CCR 情况。
采用方便抽样法抽取 27 户家庭。每个家庭必须至少有一个每日吸烟的人和一个三岁以下的孩子。在七天内,每天从孩子身上采集尿液样本。为了检验父母自我报告的吸烟行为与婴儿每日 CCR 之间的关系,采用广义估计方程(GEE)分析。
数据显示,家中有室内吸烟的婴儿的 CCR 高于家中有室外吸烟的婴儿。女孩的 CCR 高于男孩。年龄较大的婴儿的 CCR 低于年龄较小的婴儿。在家中吸烟与在家外吸烟、婴儿的性别以及婴儿的年龄共同解释了 GEE 数据分析模型中 68%的 CCR 差异。未发现 CCR 随时间的增加或减少。
研究结果表明,父母自我报告的在家中室内吸烟与室外吸烟相比,可预测三岁及以下婴儿的 CCR。女孩尿液中 CCR 浓度较高需要进一步研究。此外,在七天的时间内,婴儿的每日 CCR 没有明显的波动。