Brar Ranjeet, Nordon Ian M, Hinchliffe Robert J, Loftus Ian M, Thompson Matthew M
St George's Vascular Institute, St George's Hospital, London, UK.
Vascular. 2010 Jul-Aug;18(4):205-20. doi: 10.2310/6670.2010.00013.
Open surgery remains the gold standard by which endovascular treatment of superficial chronic venous insufficiency is measured. This meta-analysis of randomized controlled trials reviews the current evidence base, comparing open and endovascular treatment of varicose veins. Systematic review of studies reporting duplex scan follow-up after open surgical, laser (endovenous laser therapy [EVLT]), or radiofrequency (VNUS Closure device, VNUS Medical Technologies, San Jose, CA) treatment of refluxing great saphenous veins was completed. Primary outcome measures were occlusion and complication rates and time taken to resume work. No significant difference in recurrence rates at 3 months between open surgery and EVLT (RR 2.19, 95% CI 0.99-4.85, p = .05) or VNUS device (RR 7.57; 95% CI 0.42-136.02) were found. Return to work is significantly faster following VNUS (by 8.24 days; 95% CI 10.50-5.97) or EVLT (by 5.02 days; 95% CI 6.52-3.52). Endovascular treatment of varicose veins is safe and effective and offers the significant advantage of rapid recovery.
开放手术仍然是衡量浅表慢性静脉功能不全血管内治疗效果的金标准。这项随机对照试验的荟萃分析回顾了当前的证据基础,比较了开放手术和血管内治疗静脉曲张的效果。完成了对有关开放手术、激光(静脉腔内激光治疗[EVLT])或射频(VNUS闭合装置,VNUS医疗技术公司,加利福尼亚州圣何塞)治疗大隐静脉反流后进行双功超声扫描随访研究的系统评价。主要结局指标为闭塞率、并发症发生率以及恢复工作所需时间。未发现开放手术与EVLT(风险比2.19,95%可信区间0.99 - 4.85,p = 0.05)或VNUS装置(风险比7.57;95%可信区间0.42 - 136.02)在3个月时复发率有显著差异。VNUS治疗后(快8.24天;95%可信区间10.50 - 5.97)或EVLT治疗后(快5.02天;95%可信区间6.52 - 3.52)恢复工作明显更快。静脉曲张的血管内治疗安全有效,具有恢复迅速的显著优势。