Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada.
Vaccine. 2010 Aug 31;28(38):6210-20. doi: 10.1016/j.vaccine.2010.07.010. Epub 2010 Jul 17.
In response to the pandemic H1N1 influenza 2009 outbreak, many jurisdictions undertook mass immunization programs that were among the largest in recent history. The objective of this study was to determine the cost-effectiveness of the mass H1N1 immunization program in Ontario, Canada's most populous province (population 13,000,000). This analysis suggests that a mass immunization program as carried out in Ontario and many other high-income health care systems in response to H1N1 2009 was effective in preventing influenza cases and health care resource use and was also highly cost-effective despite the substantial program cost.
针对 2009 年大流行的 H1N1 流感疫情,许多司法管辖区开展了大规模免疫接种计划,这是近代史上规模最大的计划之一。本研究的目的是确定加拿大人口最多的省份(1300 万人口)安大略省大规模 H1N1 免疫计划的成本效益。本分析表明,针对 2009 年 H1N1 流感,安大略省和许多其他高收入医疗保健系统开展的大规模免疫接种计划在预防流感病例和医疗资源使用方面是有效的,尽管计划成本巨大,但也具有很高的成本效益。