Park Jung Keun, Lee Soo, Lee Ji Eun, Han Kyung-Do, Kim Ji Hyun, Yoon Jin Hee, Park Suk Won, Kim Yang-Hyun, Cho Kyung-Hwan
Department of Family Medicine, Korea University College of Medicine, Seoul, Korea.
Department of Medical Statistics, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Korean J Fam Med. 2018 Mar;39(2):90-95. doi: 10.4082/kjfm.2018.39.2.90. Epub 2018 Mar 22.
Globally, smoking is one of the biggest challenges in public health and is a known cause of several important diseases. Influenza is preventable via annual vaccination, which is the most effective and cost-beneficial method of prevention. However, subjects who smoke have some unhealthy behaviours such as alcohol, low physical activity, and low vaccination rate. In this study, we analyzed the relationship between smoking status and factors potentially related to the influenza vaccination coverage rate in the South Korean adult population.
The study included 13,565 participants aged >19 years, from 2010 to 2012 from the Korea National Health and Nutrition Examination Survey data. Univariate analyses were conducted to examine the association between influenza coverage rate and related factors. Multivariate analysis was obtained after adjusting for variables that were statistically significant.
The overall vaccination rate was 27.3% (n=3,703). Older individuals (P<0.0001), women (P<0.0001), non-smokers (P<0.0001), light alcohol drinkers (P<0.0001), the unemployed (P<0.0001), and subjects with diabetes mellitus (P<0.0001), hypercholesterolemia (P<0.0001), and metabolic syndrome (P<0.0001) had higher influenza vaccination coverage than the others. In multivariate analyses, current smokers and heavy smokers showed lower vaccination rates (odds ratio, 0.734; 95% confidence interval, 0.63-0.854).
In the current study, smokers and individuals with inadequate health-promoting behaviors had lower vaccination rates than the others did.
在全球范围内，吸烟是公共卫生领域面临的最大挑战之一，并且是多种重要疾病的已知病因。流感可通过每年接种疫苗来预防，这是最有效且具有成本效益的预防方法。然而，吸烟者存在一些不健康行为，如饮酒、身体活动量低以及疫苗接种率低。在本研究中，我们分析了韩国成年人群中吸烟状况与可能与流感疫苗接种覆盖率相关的因素之间的关系。
该研究纳入了2010年至2012年韩国国家健康与营养检查调查数据中13565名年龄大于19岁的参与者。进行单因素分析以检验流感疫苗接种覆盖率与相关因素之间的关联。在对具有统计学显著性的变量进行调整后进行多因素分析。
总体疫苗接种率为27.3%（n = 3703）。老年人（P < 0.0001）、女性（P < 0.0001）、非吸烟者（P < 0.0001）、轻度饮酒者（P < 0.0001）、失业者（P < 0.0001）以及患有糖尿病（P < 0.0001）、高胆固醇血症（P < 0.0001）和代谢综合征（P < 0.0001）的受试者的流感疫苗接种覆盖率高于其他人。在多因素分析中，当前吸烟者和重度吸烟者的疫苗接种率较低（优势比，0.734；95%置信区间，0.63 - 0.854）。
在当前研究中，吸烟者以及健康促进行为不足的个体的疫苗接种率低于其他人。
