Department of Anesthesiology, Translational Pharmaconutrition (TPN) Research Laboratories, University of Colorado Denver, Research Complex 2, Box 8602, 12700 East 19th Avenue, Aurora, CO 80045, USA.
Crit Care Clin. 2010 Jul;26(3):515-25, ix-x. doi: 10.1016/j.ccc.2010.04.006.
Glutamine (GLN) has been shown to be a key pharmaconutrient in the body's response to stress and injury. It exerts its protective effects via multiple mechanisms, including direct protection of cells and tissue from injury, attenuation inflammation, and preservation of metabolic function. Data support GLN as an ideal pharmacologic intervention to prevent or treat multiple organ dysfunction syndrome after sepsis or other injuries in the intensive care unit population. A large and growing body of clinical data shows that in well-defined critically ill patient groups GLN can be a life-saving intervention.
谷氨酰胺（GLN）已被证明是人体应对压力和损伤的关键药物营养素。它通过多种机制发挥其保护作用，包括直接保护细胞和组织免受损伤、减轻炎症和维持代谢功能。有数据支持 GLN 作为一种理想的药物干预措施，可预防或治疗重症监护病房人群中脓毒症或其他损伤后的多器官功能障碍综合征。大量不断增加的临床数据表明，在明确界定的重症患者群体中，GLN 可以是一种救命的干预措施。
