Fremont Richard D, Rice Todd W
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Meharry Medical College, Nashville, Tennessee.
Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee
Nutr Clin Pract. 2015 Jun;30(3):344-50. doi: 10.1177/0884533615578457. Epub 2015 Apr 8.
Sepsis is a common disease seen in critically ill patients. Many patients with sepsis are unable to provide nutrition for themselves, and therefore initiating artificial nutrition has become part of routine care for these patients. However, studies investigating the optimal route, composition, volume, and duration of nutrition in critically ill patients with sepsis are lacking. The best recommendations have to be extrapolated from studies in heterogeneous populations of critically ill patients or in those with syndromes such as acute lung injury or acute respiratory distress syndrome (ARDS) where sepsis is a common predisposing etiology. In this review, we summarize pertinent studies that inform clinical practice on providing artificial nutrition to critically ill patients with severe sepsis and make recommendations as to how these studies influence clinical care of these patients.
脓毒症是危重症患者中常见的疾病。许多脓毒症患者无法自行摄取营养,因此启动人工营养已成为这些患者常规治疗的一部分。然而,针对脓毒症危重症患者营养的最佳途径、成分、量及持续时间的研究尚缺乏。最佳建议不得不从针对危重症患者异质性群体或患有诸如急性肺损伤或急性呼吸窘迫综合征(ARDS)等综合征(脓毒症是常见的诱发病因)的研究中推断得出。在本综述中,我们总结了为重症脓毒症危重症患者提供人工营养的相关研究,这些研究为临床实践提供了依据,并就这些研究如何影响这些患者的临床护理提出了建议。