Kuhn G, Pohl S, Hingst V
Institut für Versuchstierkunde, Universität Heidelberg.
Berl Munch Tierarztl Wochenschr. 1991 Apr 1;104(4):130-3.
In the years 1987-1989 a bacteriological investigation of the milk was made in 44 clinically healthy postparturient bitches. In 30 animals bacteria most commonly isolated were staphylococci. 30.3% (40 samples) of the samples yielded pure cultures and 6.8% (9 samples) anacultures. Small numbers of bacteria were isolated in most of the samples; 67.4% showed moderate bacterial growth (less than or equal to 10(4)/ml sample). In vitro drug sensitivity tests revealed lincomycin, erythromycin and polymyxin B proved to be most efficient. Moreover neomycin, kanamycin and chloramphenicol showed low resistance rates while colistin sulfate and carbenicillin were less effective. A direct influence of lactiferous gland colonization with bacteria on mortality of puppies was not observed. With respect to clinical aspects, the application of antibiotics for sanitation of the lactiferous gland colonization with bacteria in clinically healthy bitches has to be considered carefully. However, for this the estimation of drug sensitivity tests is not satisfactory and should be completed by accurate bacteriological identification.
1987年至1989年期间，对44只临床健康的产后母犬的乳汁进行了细菌学调查。在30只动物中，最常分离出的细菌是葡萄球菌。30.3%（40份样本）的样本产生了纯培养物，6.8%（9份样本）为无菌培养物。大多数样本中分离出的细菌数量较少；67.4%显示出中度细菌生长（小于或等于10⁴/ml样本）。体外药敏试验表明，林可霉素、红霉素和多粘菌素B被证明是最有效的。此外，新霉素、卡那霉素和氯霉素的耐药率较低，而硫酸黏菌素和羧苄青霉素效果较差。未观察到乳腺细菌定植对幼犬死亡率有直接影响。就临床方面而言，对于临床健康母犬乳腺细菌定植的卫生处理，抗生素的应用必须谨慎考虑。然而，对于这一点，药敏试验的评估并不令人满意，应该通过准确的细菌学鉴定来完善。
