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What determines the increase in liver cell volume in the fasted-to-fed transition: glycogen or insulin?

作者信息

Agius L, Peak M, al-Habori M

出版信息

Biochem J. 1991 Jun 15;276 ( Pt 3)(Pt 3):843-5. doi: 10.1042/bj2760843.

DOI:10.1042/bj2760843
PMID:2064620
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1151082/
Abstract
摘要

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What determines the increase in liver cell volume in the fasted-to-fed transition: glycogen or insulin?在空腹到进食的转变过程中,是什么决定了肝细胞体积的增加:糖原还是胰岛素?
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Activation of glycogen synthase in myocardium induced by intermittent hypoxia is much lower in fasted than in fed rats.间歇性低氧诱导的心肌糖原合酶激活在禁食大鼠中比在喂食大鼠中低得多。
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Dietary fructose induces a wide range of genes with distinct shift in carbohydrate and lipid metabolism in fed and fasted rat liver.膳食果糖可诱导喂食和禁食大鼠肝脏中多种基因表达,碳水化合物和脂质代谢发生明显变化。
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Administration of Escherichia coli endotoxin to rat increases liver mass and hepatocyte volume in vivo.给大鼠注射大肠杆菌内毒素可在体内增加肝脏重量和肝细胞体积。
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Effects of hydration state on the synthesis and secretion of triacylglycerol by isolated rat hepatocytes. Implications for the actions of insulin and glucagon on hepatic secretion.水合状态对分离的大鼠肝细胞合成和分泌三酰甘油的影响。对胰岛素和胰高血糖素肝脏分泌作用的启示。
Biochem J. 1995 Nov 15;312 ( Pt 1)(Pt 1):57-62. doi: 10.1042/bj3120057.
5
Regulation of glycogen synthesis and glycolysis by insulin, pH and cell volume. Interactions between swelling and alkalinization in mediating the effects of insulin.胰岛素、pH值和细胞体积对糖原合成及糖酵解的调节作用。肿胀与碱化在介导胰岛素效应过程中的相互作用。
Biochem J. 1992 Mar 15;282 ( Pt 3)(Pt 3):797-805. doi: 10.1042/bj2820797.
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The role of cell swelling in the stimulation of glycogen synthesis by insulin.细胞肿胀在胰岛素刺激糖原合成中的作用。
Biochem J. 1992 Mar 15;282 ( Pt 3)(Pt 3):789-96. doi: 10.1042/bj2820789.

本文引用的文献

1
Effect of insulin on carbohydrate metabolism and on potassium in the forearm of man.胰岛素对人体前臂碳水化合物代谢及钾的影响。
J Clin Invest. 1962 Jan;41(1):108-15. doi: 10.1172/JCI104452.
2
Effect of insulin on potassium efflux from rat muscle in the presence and absence of glucose.胰岛素在有葡萄糖和无葡萄糖情况下对大鼠肌肉钾外流的影响。
Am J Physiol. 1960 May;198:1066-70. doi: 10.1152/ajplegacy.1960.198.5.1066.
3
Net potassium movement between resting muscle and plasma in man in the basal state and during the night.人体在基础状态及夜间静息肌肉与血浆之间的钾净移动情况。
J Clin Invest. 1957 May;36(5):723-9. doi: 10.1172/JCI103475.
4
Potassium exchange in the isolated diaphragm; effect of anoxia and cold.离体膈肌中的钾交换;缺氧和低温的影响。
Am J Physiol. 1954 May;177(2):211-8. doi: 10.1152/ajplegacy.1954.177.2.211.
5
Intracellular pH mediates action of insulin on glycolysis in frog skeletal muscle.细胞内pH值介导胰岛素对青蛙骨骼肌糖酵解的作用。
Am J Physiol. 1982 Jan;242(1):C87-93. doi: 10.1152/ajpcell.1982.242.1.C87.
6
Effect of graded doses of insulin on splanchnic and peripheral potassium metabolism in man.
Am J Physiol. 1980 May;238(5):E421-7. doi: 10.1152/ajpendo.1980.238.5.E421.
7
The alpha particulate liver glycogen. A morphometric approach to the kinetics of its synthesis and degradation.α颗粒肝糖原。其合成与降解动力学的形态计量学研究方法。
Biochem J. 1983 Jan 1;209(1):159-65. doi: 10.1042/bj2090159.
8
Insulin and glucagon stimulation of (Na+-K+)-ATPase transport activity in isolated rat hepatocytes.
J Biol Chem. 1981 Jul 25;256(14):7449-53.
9
The effect of potassium chloride infusion on insulin secretion in vivo.氯化钾输注对体内胰岛素分泌的影响。
Horm Metab Res. 1972 Mar;4(2):64-8. doi: 10.1055/s-0028-1094101.
10
Potassium channels in myelinated nerve. Selective permeability to small cations.有髓神经中的钾通道。对小阳离子的选择性通透性。
J Gen Physiol. 1973 Jun;61(6):669-86. doi: 10.1085/jgp.61.6.669.