Lam C S P, Ho K T
Cardiac Department, The Heart Institute, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074.
Ann Acad Med Singap. 2004 Jul;33(4):419-22.
Coronary artery ectasia (CAE) is a well-recognised, albeit rare, angiographic finding of abnormal coronary dilatation. To our best knowledge, its incidence has never been described in Singapore. We aimed to determine the incidence of CAE at our teaching hospital and to describe patient and angiographic characteristics.
Cases were identified through a search of our hospital's computer database and all records were reviewed.
Over the 10-year study period (1992-2001), 8641 patients underwent coronary angiography. CAE was diagnosed in 104 patients, giving an incidence of 1.2%. The majority (74%) were male. The median age was 54 years (range, 25 to 79 years). Sixty-six per cent of patients were Chinese, 19% Malays, 12% Indians and 3% other races. Concomitant diabetes mellitus was present in 31%, hypertension in 58% and dyslipidaemia in 63% of patients. Co-existent obstructive coronary artery disease was present in 82% of cases. The frequency of arterial involvement was: right coronary artery (RCA), 65%; left anterior descending artery (LAD), 48%; circumflex artery (CX), 43%; and left main artery (LM), 2%. CAE affected only 1 major vessel in 62% of cases and all 3 vessels in 20%. Eighteen patients were advised to undergo bypass surgery, while percutaneous coronary intervention was recommended in 26 patients.
The incidence of ectasia was 1.2%. The majority of patients were males in their sixth decade with underlying dyslipidaemia or hypertension. CAE was associated with obstructive coronary artery disease in more than 80% of cases. The RCA was most commonly affected and most patients had single vessel involvement.
冠状动脉扩张(CAE)是一种已被充分认识的血管造影表现,即冠状动脉异常扩张,尽管较为罕见。据我们所知,新加坡从未描述过其发病率。我们旨在确定我院教学医院CAE的发病率,并描述患者及血管造影特征。
通过检索我院计算机数据库确定病例,并对所有记录进行回顾。
在1992年至2001年的10年研究期间,8641例患者接受了冠状动脉造影。104例患者被诊断为CAE,发病率为1.2%。大多数(74%)为男性。中位年龄为54岁(范围25至79岁)。66%的患者为华人,19%为马来人,12%为印度人,3%为其他种族。31%的患者伴有糖尿病,58%患有高血压,63%患有血脂异常。82%的病例并存阻塞性冠状动脉疾病。动脉受累频率为:右冠状动脉(RCA)65%;左前降支动脉(LAD)48%;回旋支动脉(CX)43%;左主干动脉(LM)2%。62%的病例中CAE仅累及1支主要血管,20%累及所有3支血管。18例患者被建议接受搭桥手术,26例患者被推荐进行经皮冠状动脉介入治疗。
扩张的发病率为1.2%。大多数患者为60岁左右的男性,伴有血脂异常或高血压。超过80%的病例中CAE与阻塞性冠状动脉疾病相关。RCA最常受累,大多数患者为单支血管受累。