School of Environmental Science and Public Health, Wenzhou Medical College, Wenzhou, Zhejiang 325035, China.
Chemosphere. 2010 Aug;80(9):978-81. doi: 10.1016/j.chemosphere.2010.05.040. Epub 2010 Jun 19.
Long term exposure to arsenic can cause adverse health effects and lead to different levels of disability. The prevalence of arsenical dermatosis is as high as 40% in the Hetao Plain area of Inner Mongolia, but the association between exposure to arsenic in drinking water and the occurrence of disability has not yet been fully examined. The aim of this study was to investigate the prevalence of disability in arsenic-affected villages in Inner Mongolia, China.
A cross-sectional study was performed to examine the prevalence of disability. A total of 320 villagers in the age range of 20-39 years were interviewed and examined for disability and arsenical skin lesions. The subjects were classified into a high arsenic group (50 microg L(-1)) and a low arsenic group (<50 microg L(-1)). The relationship between levels of arsenic in drinking water and disability was analyzed using multivariate logistic regression models to estimate the odds ratios and 95% confidence intervals.
The prevalence of disability was 6.88% in the arsenic affected area of Inner Mongolia and 24.72% in the arsenic group 50 microg L(-1). A strong correlation was found between disability and arsenical skin lesions (OR=86.39, 95%CI: 25.45-293.20).
This suggests that the level of arsenic exposure is a major risk factor for disability. Further research is needed to place the results in a wider context and to determine the exact relationship between arsenic exposure and disability.
调查内蒙古砷污染区人群残疾的现患率。
采用现况研究方法,对内蒙古砷污染区 320 名 20~39 岁的村民进行了残疾和砷相关性皮肤损伤的问卷调查和检查。根据饮用水砷浓度分为高砷组(≥50μg/L)和低砷组(<50μg/L)。采用多因素 logistic 回归模型分析饮水砷与残疾的关系,计算比值比(OR)及其 95%可信区间(CI)。
内蒙古砷污染区人群残疾现患率为 6.88%,高砷组残疾现患率为 24.72%。残疾与砷相关性皮肤损伤之间存在强关联(OR=86.39,95%CI:25.45~293.20)。
砷暴露水平是导致残疾的重要危险因素。需要进一步的研究将结果置于更广泛的背景下,并确定砷暴露与残疾之间的确切关系。