Yale University School of Medicine, 34 Park Street, New Haven, CT 06519, USA.
J Pain. 2011 Jan;12(1):22-8. doi: 10.1016/j.jpain.2010.04.006. Epub 2010 Jun 20.
Differences in lifetime trauma exposure and screened symptoms of posttraumatic stress disorder (PTSD) were examined in methadone maintenance treatment (MMT) patients with a variety of pain experiences. Parametric and nonparametric statistical tests were performed on data obtained from 150 patients currently enrolled in MMT. In comparison to MMT patients reporting no pain in the previous week, those with chronic severe pain (CSP) (ie, pain lasting at least 6 months with moderate to severe pain intensity or significant pain interference) exhibited comparable levels of trauma involving sexual assault but reported significantly higher levels of trauma involving physical assault, number of traumatic events, and screened symptoms of PTSD. A third group, non-CSP MMT patients reporting some pain in the past week, differed significantly from the CSP group on number of traumatic events but reported comparable levels of sexual assault and physical assault. In comparison to men, women reported higher levels of sexual assault and were more likely to score above the cutoff on the PTSD screener but reported comparable levels of physical assault and number of traumatic events. Pain-related differences in trauma and screened symptoms of PTSD exist in MMT patients and may have implications for program planning and outreach efforts.
This article demonstrates that trauma and screened symptoms of PTSD vary as a function of sex and pain status in methadone-maintained patients. Future studies may benefit from developing and assessing interventions that address chronic pain, PTSD, and opioid dependence in MMT.
本研究考察了在接受美沙酮维持治疗(MMT)的患者中,不同的终生创伤暴露和创伤后应激障碍(PTSD)筛查症状与各种疼痛体验之间的差异。对目前正在接受 MMT 的 150 名患者的数据进行了参数和非参数统计检验。与上周报告无疼痛的 MMT 患者相比,慢性严重疼痛(CSP)(即疼痛持续至少 6 个月,疼痛强度为中度至重度或疼痛干扰显著)患者的性侵犯相关创伤程度相当,但身体攻击、创伤事件数量和 PTSD 筛查症状的报告水平显著较高。第三组为过去一周报告有一些疼痛的非 CSP MMT 患者,与 CSP 组在创伤事件数量上存在显著差异,但性侵犯和身体攻击的报告水平相当。与男性相比,女性报告的性侵犯程度更高,更有可能在 PTSD 筛查器上的得分超过临界值,但报告的身体攻击和创伤事件数量相当。在 MMT 患者中,疼痛相关的创伤和 PTSD 筛查症状存在差异,这可能对项目规划和外展工作具有重要意义。
本文表明,在接受美沙酮维持治疗的患者中,创伤和 PTSD 筛查症状因性别和疼痛状况而异。未来的研究可能受益于开发和评估干预措施,以解决 MMT 患者的慢性疼痛、PTSD 和阿片类药物依赖问题。