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美沙酮维持治疗患者特质性乐观与精神病理学和疼痛的相关性。

Psychopathology and pain correlates of dispositional optimism in methadone-maintained patients.

机构信息

Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA.

出版信息

Am J Addict. 2012 Nov;21 Suppl 1(0 1):S56-62. doi: 10.1111/j.1521-0391.2012.00293.x.

Abstract

BACKGROUND AND OBJECTIVES

Although higher levels of dispositional optimism are associated with decreased levels of psychopathology and pain, and higher levels of mental health functioning-important outcomes in opioid treatment programs-a paucity of studies has examined dispositional optimism among individuals with opioid use disorders. The aim of this study was to examine the clinical correlates (i.e., psychopathology, pain status) of dispositional optimism in opioid dependent patients enrolled in methadone maintenance treatment (MMT).

METHODS

A survey targeting demographics, pain, psychopathology, and dispositional optimism was administered to 150 MMT patients.

RESULTS

In multivariable analyses, higher levels of dispositional optimism were significantly associated with lower levels of: depression, screened personality disorder criteria, screened symptoms of posttraumatic stress disorder, and pain-related emotional strain. In comparison to those without a history of chronic pain (ie, noncancer related physical pain lasting at least 3 months), MMT patients who reported either lifetime or current chronic pain exhibited significantly lower levels of dispositional optimism.

CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE

The associations among higher levels of dispositional optimism, lower levels of psychopathology, and lower pain-related emotional strain suggest that research focusing on the efficacy of specific interventions to promote dispositional optimism in MMT patients is warranted.

摘要

背景和目的

尽管性格乐观与精神病理学和疼痛程度降低以及心理健康功能水平升高有关,而这些都是阿片类药物治疗项目中的重要结果,但很少有研究关注阿片类药物使用障碍患者的性格乐观。本研究旨在探讨参加美沙酮维持治疗(MMT)的阿片类药物依赖患者性格乐观的临床相关性(即精神病理学、疼痛状况)。

方法

针对人口统计学、疼痛、精神病理学和性格乐观,对 150 名 MMT 患者进行了一项调查。

结果

在多变量分析中,性格乐观水平较高与以下因素呈显著负相关:抑郁、筛查人格障碍标准、筛查创伤后应激障碍症状和与疼痛相关的情绪压力。与没有慢性疼痛病史的患者(即持续至少 3 个月的非癌症相关躯体疼痛)相比,报告有终身或当前慢性疼痛的 MMT 患者的性格乐观水平显著较低。

结论和科学意义

性格乐观水平较高、精神病理学水平较低以及与疼痛相关的情绪压力较低之间的关联表明,有必要针对 MMT 患者开展具体干预措施以促进性格乐观的疗效研究。

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