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[背部微循环室活体观察技术及其应用]

[Intravital observation technology of dorsal microcirculatory chamber and its application].

作者信息

Lu Liqiong, Wang Xiang

机构信息

Bioengineering College, Chongqing University, Chongqing 400030, China.

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2010 Jun;27(3):688-91.

PMID:20649045
Abstract

Observation of microcirculation plays an important role on the basic research and clinical diagnosis. However, an observation as such on the anesthetized patient will cause stress reaction, thus it will affect normal physiological state and interfere experimental results. At present, a method adopting dorsal microcirculatory chamber (DMC) to do in vivo observation in an unanesthetized state can eliminate the influence of anesthesia. Based on the research reports and practical applications of this method abroad, we summarize, in here, the configuration, function, observation techniques; the application of DMC; and the research states of microcirculation observation.

摘要

微循环观察在基础研究和临床诊断中发挥着重要作用。然而,对麻醉患者进行此类观察会引发应激反应,进而影响正常生理状态并干扰实验结果。目前,一种采用背部微循环室(DMC)在未麻醉状态下进行体内观察的方法可消除麻醉的影响。基于国外对该方法的研究报道及实际应用,我们在此总结DMC的构造、功能、观察技术;DMC的应用;以及微循环观察的研究现状。

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