Department of Ophthalmology, University Hospital of Heraklion, Crete, Greece.
Clin Exp Ophthalmol. 2010 Jul;38(5):444-8. doi: 10.1111/j.1442-9071.2010.02275.x.
To evaluate differences between Goldmann Applanation Tonometry (GAT) and Dynamic Controur Tonometry (DCT) in eyes with pseudoexfoliation syndrome (PEX).
Thirty-eight patients (38 eyes) with PEX in both eyes (pseudoexfoliative group, PG) as well as 19 patients (19 eyes) without PEX in either eye (control group, CG), were included. All eyes were phakic. GAT, DCT, the central corneal thickness (CCT) and the axial length of the eyeball (AL) were measured and the difference between GAT and DCT (dIOP) was calculated. Differences in dIOP between CG and PG and correlations of dIOP with CCT and AL were examined.
dIOP was significantly (P = 0.02) higher in PG (mean value 3.69 mmHg), compared with CG (mean value 2.15 mmHg). In PG (but not in CG), dIOP was also significantly correlated with AL but not with CCT.
The fact that dIOP was significantly higher in PG than in CG implies that PEX may affect ocular biomechanical properties. The significant association of dIOP with AL but not with CCT is in agreement with previous reports and complies with the fact that pseudoexfoliative material is not deposited in corneal stroma.
评估 Goldmann 压平眼压计(GAT)和动态轮廓眼压计(DCT)在假性剥脱综合征(PEX)眼中的差异。
纳入双眼均患有 PEX 的 38 名患者(38 只眼)(假性剥脱组,PG)以及双眼均无 PEX 的 19 名患者(19 只眼)(对照组,CG)。所有眼睛均为透明晶状体。测量 GAT、DCT、中央角膜厚度(CCT)和眼球轴向长度(AL),并计算 GAT 和 DCT 之间的差异(dIOP)。检查 CG 和 PG 之间的 dIOP 差异以及 dIOP 与 CCT 和 AL 的相关性。
PG(平均值 3.69mmHg)的 dIOP 明显高于 CG(平均值 2.15mmHg)(P=0.02)。在 PG(但不是 CG)中,dIOP 也与 AL 显著相关,但与 CCT 无关。
PG 中的 dIOP 明显高于 CG,这表明 PEX 可能影响眼生物力学特性。dIOP 与 AL 显著相关,而与 CCT 无关,这与之前的报道一致,并且符合假性剥脱物质不沉积在角膜基质的事实。