Pramaditya Herlangga, Tjokroprawiro Brahmana Askandar
Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga/Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga/Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
Int J Surg Case Rep. 2022 Nov;100:107758. doi: 10.1016/j.ijscr.2022.107758. Epub 2022 Oct 24.
Leiomyosarcoma (LMS) is a malignant tumor of the uterine smooth muscle. It is highly aggressive and accounts for 1 % of all uterine malignancies. Symptoms often include a rapidly growing mass, with an average course of illness ranging from six to eight months. Leiomyosarcomas are rare in younger individuals.
A 31-year-old nulliparous woman was diagnosed with a suspected malignant ovarian tumor. A unilateral salpingo-oophorectomy and surgical staging were planned to preserve the patient's fertility. However, the large solid mass was found to be arising from the uterus during surgery. In light of the preference for fertility preservation, a myomectomy was performed, with subsequent pathology results showing a malignant leiomyosarcoma. Following counseling and discussion with the patient and her spouse, follow-up surgery was performed to ensure a free surgical margin.
Leiomyosarcomas at a young age is very rare, and early diagnosis is quite a challenge, especially when the tumor characteristics are not atypical. Thus, surgical evaluation and staging are paramount.
Surgical diagnosis of any mass with a history of rapid enlargement and characteristics of malignancy is very important, especially when anatomical landmarks are distorted due to the enlarged mass.
平滑肌肉瘤(LMS)是子宫平滑肌的恶性肿瘤。它具有高度侵袭性,占所有子宫恶性肿瘤的1%。症状通常包括迅速增大的肿块,平均病程为六至八个月。平滑肌肉瘤在年轻个体中较为罕见。
一名31岁未生育的女性被诊断为疑似恶性卵巢肿瘤。计划进行单侧输卵管卵巢切除术和手术分期以保留患者的生育能力。然而,手术中发现这个大的实性肿块起源于子宫。鉴于保留生育能力的意愿,进行了肌瘤切除术,随后的病理结果显示为恶性平滑肌肉瘤。在与患者及其配偶进行咨询和讨论后,进行了后续手术以确保手术切缘阴性。
年轻患者的平滑肌肉瘤非常罕见,早期诊断颇具挑战,尤其是当肿瘤特征不典型时。因此,手术评估和分期至关重要。
对任何有快速增大病史且具有恶性特征的肿块进行手术诊断非常重要,尤其是当肿块增大导致解剖标志变形时。