Rizwan Tehlil, Ahmed Jawad, Shaikh Fahad H, Malik Farheen, Ullah Shuah
Internal Medicine, Dow University of Health Sciences, Karachi, PAK.
General Surgery/Urology, Sindh Institute of Urology and Transplantation, Karachi, PAK.
Cureus. 2020 Aug 30;12(8):e10146. doi: 10.7759/cureus.10146.
Leiomyosarcoma, primarily a tumor of smooth muscle origin, frequently originates from the uterus, retroperitoneum, and intra-abdominal region. Rarely, the tumor may arise from the conjunctiva, inferior vena cava, or oral cavity. Here we report a case of a 65-year-old male patient who presented with a swelling in the posterior thigh for six months. The swelling was progressively increasing in size for the last two months. Examination of thigh showed a swelling of 20×30 cm in size, which was firm, non-compressible, immobile, and not transilluminating. CT scan showed no metastasis in the liver, lung, or bone. The histopathology report showed poorly differentiated leiomyosarcoma involving the muscles of the posterior compartment of the left thigh. The tumor was resected, and the patient was referred to rehabilitation clinic. Early diagnosis of such cases is essential to improve the outcome in patients as these tumors can metastasize early.
平滑肌肉瘤主要起源于平滑肌，常见于子宫、腹膜后和腹腔内区域。罕见情况下，肿瘤可起源于结膜、下腔静脉或口腔。在此，我们报告一例65岁男性患者，其大腿后部肿胀6个月。在过去两个月中，肿胀大小逐渐增大。检查发现大腿有一个大小为20×30厘米的肿块，质地坚硬，不可压缩，固定不动，不透光。CT扫描显示肝脏、肺或骨骼无转移。组织病理学报告显示为低分化平滑肌肉瘤，累及左大腿后肌群。肿瘤被切除，患者被转至康复诊所。此类病例的早期诊断对于改善患者预后至关重要，因为这些肿瘤可早期转移。
