[拉巴特穆罕默德五世军事教学医院使用的防腐剂的抗菌活性]

[Antibacterial activity of antiseptics used at Military Teaching Hospital Mohamed V of Rabat].

作者信息

Essayagh Touria, Elameri Abdouelouhab, Zohoun Alban, Miloudi Mouhcine, Elhamzaoui Sakina

机构信息

Laboratoire de bactériologie, Hôpital militaire d'instruction Mohamed-V, Rabat, Morocco.

出版信息

Ann Biol Clin (Paris). 2010 Jul-Aug;68(4):421-7. doi: 10.1684/abc.2010.0447.

DOI:10.1684/abc.2010.0447

PMID:20650737

Abstract

Antiseptics have a major role against the infections and their prevention. The good management of antiseptics allows the reduction of antibiotics use and thus the emergence of resistant bacterial strains. The evaluation of the antibacterial activity of three antiseptics (povidone iodine [PVPI], iodized alcohol and alcohol 70 degrees) used at HMIMV and taken from pharmacy was based on AFNOR method NF T 72-150. The analysis of their chemical properties were done by standardized methods (manganimetry, Bunsen's method, test to determine sodium thiosulfate levels [or sodium thiosulfate test] and Guy Lussac alcoholmeter). Our results were compared with those obtained in another two university hospitals of Rabat: Hospital of Speciality and Ibn Sina. The frequencies of resistant bacterial strains were respectively 4.6%, 30.7% and 15.4% to PVPI, alcohol iodized and alcohol 70 degrees . Our results have shown that the PVPI is the best antiseptic in our hospital.

摘要

防腐剂在抗感染及其预防方面发挥着重要作用。合理使用防腐剂可减少抗生素的使用，从而降低耐药菌株的出现。本研究基于法国标准化协会（AFNOR）方法NF T 72 - 150，对在穆罕默德五世军事医院（HMIMV）药房获取的三种防腐剂（聚维酮碘[PVPI]、碘酒和70度酒精）的抗菌活性进行评估。通过标准化方法（高锰酸钾滴定法、本生法、硫代硫酸钠含量测定试验[或硫代硫酸钠试验]和盖吕萨克酒精比重计）对其化学性质进行分析。我们的结果与拉巴特另外两家大学医院（专科医院和伊本·西那医院）的结果进行比较。对PVPI、碘酒和70度酒精耐药的菌株频率分别为4.6%、30.7%和15.4%。我们的结果表明，PVPI是我院最佳的防腐剂。