子宫平滑肌瘤中13号染色体缺失。
Deletion of chromosome 13 in leiomyomas of the uterus.
作者信息
Meloni A M, Surti U, Sandberg A A
机构信息
Cancer Center, Southwest Biomedical Research Institute and Genetrix, Scottsdale, AZ 85251.
出版信息
Cancer Genet Cytogenet. 1991 Jun;53(2):199-203. doi: 10.1016/0165-4608(91)90096-d.
PMID:2065294
Abstract
We report two cases of leiomyomas of the uterus with a deletion of the long arm of chromosome 13. To our knowledge this cytogenetic abnormality as a single change has not been reported previously. One of our cases showed a del(13)(q14q32) and the other a del(13)(q13q33). We discuss the cases and compare our findings with previous ones reported in the literature.
摘要
我们报告了两例子宫平滑肌瘤病例，其13号染色体长臂存在缺失。据我们所知，这种细胞遗传学异常作为单一变化此前尚未见报道。我们的一例病例显示为del(13)(q14q32)，另一例为del(13)(q13q33)。我们对这些病例进行了讨论，并将我们的发现与文献中先前报道的病例进行了比较。
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