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A new cytogenetic subgroup in uterine leiomyoma is characterized by a deletion of the long arm of chromosome 3.

作者信息

Dal Cin P, Moerman P, Deprest J, Brosens I, Van den Berghe H

机构信息

Center for Human Genetics, University of Leuven, Belgium.

出版信息

Genes Chromosomes Cancer. 1995 Jul;13(3):219-20. doi: 10.1002/gcc.2870130313.

DOI:10.1002/gcc.2870130313
PMID:7669743
Abstract

Our cytogenetic findings in 175 uterine leiomyomas revealed 52 tumors with clonal chromosome abnormalities, eight of which did not belong to any well-delineated cytogenetic abnormal subgroup. However, an interstitial deletion of the long arm of chromosome 3 was found, as the sole chromosome abnormality, in three cases. We believe that this involvement of 3q is significant enough to consider it as a new cytogenetic subgroup of uterine leiomyoma.

摘要

相似文献

1
A new cytogenetic subgroup in uterine leiomyoma is characterized by a deletion of the long arm of chromosome 3.
Genes Chromosomes Cancer. 1995 Jul;13(3):219-20. doi: 10.1002/gcc.2870130313.
2
HMGIC expressed in a uterine leiomyoma with a deletion of the long arm of chromosome 7 along with a 12q14-15 rearrangement but not in tumors showing del(7) as the sole cytogenetic abnormality.HMGIC在一个伴有7号染色体长臂缺失以及12q14 - 15重排的子宫平滑肌瘤中表达,但在那些显示del(7)作为唯一细胞遗传学异常的肿瘤中不表达。
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3
Involvement of 10q22 in leiomyoma.
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4
Characteristic chromosome abnormalities, including rearrangements of 6p, del(7q), +12, and t(12;14), in 44 uterine leiomyomas.44例子宫平滑肌瘤中存在特征性染色体异常,包括6p重排、7q缺失、+12和t(12;14) 。
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Deletion of chromosome 13 in leiomyomas of the uterus.子宫平滑肌瘤中13号染色体缺失。
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6
Chromosome 7 biclonality in uterine leiomyoma.子宫平滑肌瘤中的7号染色体双克隆性
Cancer Genet Cytogenet. 1993 May;67(1):59-64. doi: 10.1016/0165-4608(93)90045-n.
7
Trisomy 12 in uterine leiomyomas. A new cytogenetic subgroup.子宫平滑肌瘤中的12号染色体三体。一个新的细胞遗传学亚组。
Cancer Genet Cytogenet. 1990 Mar;45(1):63-6. doi: 10.1016/0165-4608(90)90067-k.
8
Translocations in 7q22 define a critical region in uterine leiomyomata.7q22 易位确定了子宫平滑肌瘤中的一个关键区域。
Cancer Genet Cytogenet. 1994 Oct;77(1):65-8. doi: 10.1016/0165-4608(94)90151-1.
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Uterine leiomyoma cytogenetics. II. Report of forty cases.子宫平滑肌瘤细胞遗传学。II. 40例报告。
Cancer Genet Cytogenet. 1991 Jun;53(2):247-56. doi: 10.1016/0165-4608(91)90101-y.
10
Deletion 7q22 in uterine leiomyoma. A cytogenetic review.子宫平滑肌瘤中的7q22缺失:细胞遗传学综述
Cancer Genet Cytogenet. 1993 Nov;71(1):1-6. doi: 10.1016/0165-4608(93)90195-r.

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