Christiana Care Health System, Newark, DE, USA.
Acad Emerg Med. 2010 Jul;17(7):718-22. doi: 10.1111/j.1553-2712.2010.00796.x.
The authors hypothesized that vital sign abnormalities detected in the emergency department (ED) can be used to forecast clinical deterioration occurring within 24 hours of hospital admission.
This was a retrospective case-control study performed after implementation of a hospitalwide rapid response team (RRT) system. Inclusion criteria for study patients consisted of age > or = 18 years, admission to the general floor though the ED, and RRT activation and subsequent transfer to a higher level of care in the first 24 hours. Control patients were > or =18 years, were admitted to the floor though the ED, never required RRT or transfer to a higher level of care, and were matched to cases by risk of mortality. Multilevel logistic regression was used to model the odds of an adverse outcome as a function of race and sex, respiratory rate (RR), heart rate (HR), and systolic (sBP) and diastolic blood pressure (dBP) at time of transfer from the ED.
A total of 74 cases and 246 controls were used. RR (odds ratio [OR] = 2.79 per 10-point change, 95% confidence interval [CI] = 1.41 to 5.51) and to a lesser extent dBP (OR = 0.81, 95% CI = 0.67 to 0.97) contributed significantly to the odds of intensive care unit (ICU) or intermediate care transfer within 24 hours of admission; HR (OR = 1.15, 95% CI = 0.98 to 1.37) did not.
Emergency department RR preceding floor transfer appears to have a significant relationship to the need for ICU or intermediate care transfer in the first 24 hours of hospital admission.
作者假设在急诊科(ED)发现的生命体征异常可以用于预测入院后 24 小时内的临床恶化。
这是一项在全院快速反应团队(RRT)系统实施后进行的回顾性病例对照研究。研究患者的纳入标准为年龄≥18 岁,通过 ED 入院到普通病房,并且在头 24 小时内激活 RRT 并随后转至更高水平的护理。对照患者≥18 岁,通过 ED 入院到病房,从未需要 RRT 或转至更高水平的护理,并且与病例按死亡率匹配。使用多水平逻辑回归模型来模拟不良结局的可能性,作为种族和性别、呼吸率(RR)、心率(HR)、收缩压(sBP)和舒张压(dBP)在从 ED 转移时的函数。
共纳入 74 例病例和 246 例对照。RR(优势比[OR]每 10 点变化 2.79,95%置信区间[CI]为 1.41 至 5.51)和在较小程度上 dBP(OR = 0.81,95%CI = 0.67 至 0.97)对 ICU 或中间护理在入院后 24 小时内转移的可能性有显著贡献;HR(OR = 1.15,95%CI = 0.98 至 1.37)则没有。
在转入普通病房之前,ED 的 RR 似乎与入院后 24 小时内需要 ICU 或中间护理的转移有显著关系。