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健胃愈疡片治疗消化性溃疡

[Treatment of peptic ulcer with jian-wei yu-wang tablets].

作者信息

Li J B, Jin Y Q

机构信息

Institute of Integrated Traditional Chinese and Western Medicine, Hunan Medical University, Changsha.

出版信息

Zhong Xi Yi Jie He Za Zhi. 1991 Mar;11(3):141-3, 131-2.

PMID:2065391
Abstract

This article reports the results of second stage clinical trial on the treatment of peptic ulcer with jian-wei yu-yang (JWYY) tablets in comparison with a control group treated with ranitidine. The results showed that the cure rate for JWYY tablet group was 62.4% and its effective rate was 93. 8% in 354 cases, whereas the cure rate of the control group was 50.7% and its effective rate was 86. 4% in 140 cases. The differences between these two groups were highly significant (P less than 0.01). Based on syndrome differentiation, optimal effect was reached in treating liver stagnation and spleen deficiency syndrome and disharmony of liver and stomach syndrome. After one year follow up studies of the therapeutic effect, the recurrence rate of the JWYY tablet group was 17.7%, while that of the ranitidine group was 54.1%. In addition, JWYY tablet had no side-effects. These data indicated that JWYY tablets were a more effective therapeutic remedy for peptic ulcer.

摘要

本文报道了健胃愈疡片治疗消化性溃疡的二期临床试验结果,并与雷尼替丁治疗的对照组进行了比较。结果显示,健胃愈疡片组354例患者的治愈率为62.4%,有效率为93.8%;而对照组140例患者的治愈率为50.7%,有效率为86.4%。两组之间的差异具有高度显著性(P小于0.01)。根据辨证论治,治疗肝郁脾虚证和肝胃不和证效果最佳。对治疗效果进行一年的随访研究后,健胃愈疡片组的复发率为17.7%,而雷尼替丁组为54.1%。此外,健胃愈疡片无副作用。这些数据表明,健胃愈疡片是治疗消化性溃疡更有效的药物。

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