The Rockefeller University, New York, NY 10065, USA.
Cell. 2010 Jul 23;142(2):184-8. doi: 10.1016/j.cell.2010.07.004.
Single-celled organisms monitor cell geometry and use this information to control cell division. Such geometry-sensing mechanisms control both the decision to enter into cell division and the physical orientation of the chromosome segregation machinery, suggesting that signals controlling cell division may be linked to the mechanisms that ensure proper chromosome segregation.
单细胞生物监测细胞的几何形状,并利用这些信息来控制细胞分裂。这种几何形状感应机制控制着进入细胞分裂的决定以及染色体分离机制的物理方向,这表明控制细胞分裂的信号可能与确保正确染色体分离的机制有关。