胞质分裂中收缩环缢缩和膜运输的分子机制。
Molecular mechanisms of contractile-ring constriction and membrane trafficking in cytokinesis.
作者信息
Gerien Kenneth S, Wu Jian-Qiu
机构信息
Department of Molecular Genetics, Columbus, OH, USA.
Ohio State Biochemistry Program, Columbus, OH, USA.
出版信息
Biophys Rev. 2018 Dec;10(6):1649-1666. doi: 10.1007/s12551-018-0479-3. Epub 2018 Nov 17.
Abstract
In this review, we discuss the molecular mechanisms of cytokinesis from plants to humans, with a focus on contribution of membrane trafficking to cytokinesis. Selection of the division site in fungi, metazoans, and plants is reviewed, as well as the assembly and constriction of a contractile ring in fungi and metazoans. We also provide an introduction to exocytosis and endocytosis, and discuss how they contribute to successful cytokinesis in eukaryotic cells. The conservation in the coordination of membrane deposition and cytoskeleton during cytokinesis in fungi, metazoans, and plants is highlighted.
摘要
在本综述中，我们讨论了从植物到人类的胞质分裂分子机制，重点关注膜运输对胞质分裂的作用。综述了真菌、后生动物和植物中分裂位点的选择，以及真菌和后生动物中收缩环的组装和收缩。我们还介绍了胞吐作用和胞吞作用，并讨论它们如何促进真核细胞中的成功胞质分裂。强调了真菌、后生动物和植物在胞质分裂过程中膜沉积与细胞骨架协调方面的保守性。
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