Detweiler R E, Katz R L, Alapat C, el-Naggar A, Ordóñez N
Department of Pathology, University of Texas M.D. Anderson Cancer Center, Houston 77030.
Diagn Cytopathol. 1991;7(2):163-71. doi: 10.1002/dc.2840070213.
Two cases of primary malignant lymphoma of the thyroid were diagnosed by fine-needle aspiration biopsy. In addition to morphologic evaluation performed on direct smears, immunophenotyping, flow cytometry, and molecular studies were performed on the aspirated material. These additional studies made a clear distinction between lymphoma and Hashimoto's thyroiditis, which may present a similar cytologic picture.
两例原发性甲状腺恶性淋巴瘤通过细针穿刺活检得以诊断。除了对直接涂片进行形态学评估外，还对抽吸物进行了免疫表型分析、流式细胞术和分子研究。这些额外的研究明确区分了淋巴瘤和桥本甲状腺炎，后者可能呈现相似的细胞学表现。
