Rheumatology Unit, Istituto Ortopedico Rizzoli, Bologna, Italy.
Osteoarthritis Cartilage. 2010 Oct;18(10):1263-8. doi: 10.1016/j.joca.2010.06.006. Epub 2010 Jul 23.
To examine ultrasound (US) features of synovitis in hand osteoarthritis (OA) joints, and to evaluate their relationship with radiological damage severity and US-detected cartilage thickness.
US examination was carried out on 14 joints of both hands of 25 patients with symptomatic hand OA (HOA) and 10 age- and sex-matched control subjects. US-detected features were: synovial hypertrophy, effusion, power Doppler signal (PDS), cartilage thickness. Conventional hand radiographs were scored utilizing the Kellgren-Lawrence and Kallman systems. HOA patients were divided into two subsets: non-erosive and erosive.
Among the three groups of subjects studied, erosive OA showed the highest values of radiological scores and the highest prevalence of US-detected synovitis. Joints positive for US synovitis features (above all PDS) had higher radiological scores and lower cartilage thickness, while joints with X-ray detected central erosions [the hallmark of erosive HOA were more likely to present PDS positivity. US measured cartilage thickness inversely correlated with radiological damage scores.
US-detected synovitis is present in about 10% of HOA finger joints and is associated with more severe radiological damage and reduced cartilage thickness. PDS and cartilage thickness (mm) may represent two innovative additional information tools provided by ultrasonography in HOA evaluation.
探讨手骨关节炎（OA）关节滑膜炎的超声（US）表现，并评估其与放射学损伤严重程度和 US 检测到的软骨厚度的关系。
对 25 例手部症状性 OA（HOA）患者和 10 例年龄和性别匹配的对照组患者的双手 14 个关节进行 US 检查。US 检测到的特征包括：滑膜肥厚、积液、能量多普勒信号（PDS）、软骨厚度。采用 Kellgren-Lawrence 和 Kallman 系统对手部常规 X 线片进行评分。将 HOA 患者分为非侵蚀性和侵蚀性两组。
在三组研究对象中，侵蚀性 OA 的放射学评分最高，US 检测到滑膜炎的患病率最高。存在 US 滑膜炎特征（尤其是 PDS）的关节放射学评分更高，软骨厚度更低，而 X 射线检测到中央侵蚀的关节[侵蚀性 HOA 的标志]更有可能出现 PDS 阳性。US 测量的软骨厚度与放射学损伤评分呈负相关。
约 10%的 HOA 手指关节存在 US 检测到的滑膜炎，与更严重的放射学损伤和软骨厚度降低有关。PDS 和软骨厚度（mm）可能代表超声在 HOA 评估中提供的两种创新的额外信息工具。
