Department of Radiology, Massachusetts General Hospital Neuroradiology, GRB-273A, 55 Fruit Street, Boston, MA 02114, USA.
Skeletal Radiol. 2011 Aug;40(8):1065-72. doi: 10.1007/s00256-010-1002-5. Epub 2010 Jul 25.
This paper assesses interscan, interreader, and intrareader variability of C-arm CT and compares it to that of flat-panel volume-CT (fpVCT) and high-definition multi-detector-CT (HD-MDCT).
Five cadaver knee specimens were imaged using C-arm-CT, fpVCT, and HD-MDCT. Apparent (app.) trabecular bone volume fraction (BV/TV), app. trabecular number (TbN), app. trabecular spacing (TbSp), and app. trabecular thickness (TbTh) of the proximal tibia were measured by three readers. Interreader, intrareader, and interscan variability for C-arm CT was expressed as coefficient of variation (CV), standard deviation (SD), and intraclass correlation coefficient (ICC).
With the exception of app.TbSp (CV: 7.05-9.35%, SD: 0.06-0.09, ICC: 0.89-0.94), the variability of C-arm CT was low (CV: 2.41-6.43%, SD: 0.01-0.048, ICC: 0.65-0.98). Its interreader reliability (CV: 2.66-4.55%, SD: 0.01-0.03, ICC: 0.81-0.95) was comparable to that of HD-MDCT (CV: 2.41-4.08%, SD: 0.014-0.016, ICC: 0.95-0.96), and fpVCT (CV: 3.13-5.63%, SD: 0.009-0.036, ICC: 0.64-0.98) for all parameters except app.TbSp.
C-arm CT is a reliable method for assessing trabecular bone architectural parameters with the exception of app.TbSp due to spatial resolution limitation.
本文评估了 C 臂 CT 的扫描间、读者间和读者内变异性，并将其与平板容积 CT（fpVCT）和高清多探测器 CT（HD-MDCT）进行了比较。
对 5 个尸体膝关节标本进行 C 臂 CT、fpVCT 和 HD-MDCT 成像。由 3 位读者测量胫骨近端的表观（app.）骨小梁体积分数（BV/TV）、app. 骨小梁数量（TbN）、app. 骨小梁间距（TbSp）和 app. 骨小梁厚度（TbTh）。C 臂 CT 的读者间、读者内和扫描间变异性用变异系数（CV）、标准差（SD）和组内相关系数（ICC）表示。
除了 app.TbSp（CV：7.05-9.35%，SD：0.06-0.09，ICC：0.89-0.94）外，C 臂 CT 的变异性较低（CV：2.41-6.43%，SD：0.01-0.048，ICC：0.65-0.98）。其读者间可靠性（CV：2.66-4.55%，SD：0.01-0.03，ICC：0.81-0.95）与 HD-MDCT（CV：2.41-4.08%，SD：0.014-0.016，ICC：0.95-0.96）和 fpVCT（CV：3.13-5.63%，SD：0.009-0.036，ICC：0.64-0.98）相当，除了 app.TbSp 外，所有参数的可靠性均相当。
由于空间分辨率限制，C 臂 CT 是评估骨小梁结构参数的可靠方法，app.TbSp 除外。
