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利用海德堡视网膜断层扫描仪 II 评估健康马来成年人的视盘参数。

Assessment of optic disc parameters among healthy adult Malays by Heidelberg Retinal Tomograph II.

机构信息

Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.

出版信息

Clin Exp Ophthalmol. 2011 Jan;39(1):15-22. doi: 10.1111/j.1442-9071.2010.02385.x.

Abstract

BACKGROUND

This study aims to assess the optic disc characteristics in healthy adult Malays and to correlate them with age, gender and refractive errors.

DESIGN

Cross-sectional study.

PARTICIPANTS

A total of 200 voluntary participants (106 women and 94 men) among Malay students aged 20 to 37 years at Health Campus, Universiti Sains Malaysia.

METHODS

The relationship between Heidelberg Retinal Tomograph parameters with age, gender and refractive error were analysed with correlation tests and multiple linear regression analyses.

MAIN OUTCOME MEASURES

Twelve parameters, that is, disc area, rim area, cup area, cup to disc area, cup volume, rim volume, height variation contour, cup shape measure, mean cup depth, maximum cup depth, mean retinal nerve fibre layer thickness and retinal nerve fibre layer cross-sectional area.

RESULTS

Disc area, rim area and cup : disc area ratio averaged 2.24 ± 0.52 (mean ± standard deviation), 1.64 ± 0.32 and 0.25 ± 0.12 mm(2) , respectively. Five parameters (disc area, cup area, cup volume, cup : disc area ratio and mean retinal nerve fibre layer thickness) showed statistically significant difference between men and women. Age was negatively and significantly correlated with rim area with coefficient r = -0.21, P = 0.003. All optic disc parameters were significantly correlated (P < 0.05) with disc area, except cup shape measure.

CONCLUSIONS

One or more of optic disc parameters were affected significantly by age, gender and disc area in healthy adult Malays' eyes. These factors need to be considered during the evaluation of optic disc.

摘要

背景

本研究旨在评估健康马来成年人的视盘特征,并将其与年龄、性别和屈光不正相关联。

设计

横断面研究。

参与者

共 200 名自愿参与者(106 名女性和 94 名男性),均为马来西亚理科大学健康校园的 20 至 37 岁马来族学生。

方法

使用相关测试和多元线性回归分析,分析海德堡视网膜断层扫描仪参数与年龄、性别和屈光不正的关系。

主要观察指标

十二个参数,即视盘面积、视盘边缘面积、杯面积、杯盘比、杯容积、视盘边缘容积、高度变化轮廓、杯形测量、平均杯深度、最大杯深度、平均视网膜神经纤维层厚度和视网膜神经纤维层横截面积。

结果

视盘面积、视盘边缘面积和杯盘比平均为 2.24 ± 0.52(均值 ± 标准差)、1.64 ± 0.32 和 0.25 ± 0.12 mm²。五个参数(视盘面积、杯面积、杯容积、杯盘比和平均视网膜神经纤维层厚度)在男女之间存在统计学差异。年龄与视盘边缘面积呈负相关,相关系数 r = -0.21,P = 0.003。所有视盘参数均与视盘面积显著相关(P < 0.05),除杯形测量外。

结论

在健康马来成年人的眼中,一个或多个视盘参数受到年龄、性别和视盘面积的显著影响。在评估视盘时需要考虑这些因素。

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