Iwamoto Tomoyuki, Suzuki Nao, Tanabe Kazunari, Takeshita Toru, Hirofuji Takao
Section of General Dentistry, Department of General Dentistry, Fukuoka Dental College, Fukuoka, Japan.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Aug;110(2):201-8. doi: 10.1016/j.tripleo.2010.03.032.
The objective of this study was to evaluate whether oral administration of lactobacilli alters the degree of halitosis and clinical conditions associated with halitosis.
Twenty patients with genuine halitosis were given 2.0 x 10(9)Lactobacillus salivarius WB21 and xylitol in tablet form daily. Oral malodor and clinical parameters were evaluated at the same time of day for each patient after 2 and 4 weeks.
All 20 patients were positive for L. salivarius DNA in their saliva at 2 weeks, although 12 patients were negative for this organism at baseline. Oral malodor parameters significantly decreased at 2 weeks in the subjects with physiologic halitosis. The scores of an organoleptic test and bleeding on probing significantly decreased at 4 weeks in the subjects with oral pathologic halitosis.
Oral administration of probiotic lactobacilli primarily improved physiologic halitosis and also showed beneficial effects on bleeding on probing from the periodontal pocket.
本研究的目的是评估口服乳酸菌是否会改变口臭程度以及与口臭相关的临床状况。
20名真性口臭患者每天服用2.0×10⁹唾液乳杆菌WB21和木糖醇片剂。在2周和4周后，于每天同一时间对每位患者的口腔异味和临床参数进行评估。
2周时，所有20名患者唾液中的唾液乳杆菌DNA均呈阳性，尽管12名患者在基线时该菌呈阴性。生理性口臭患者在2周时口腔异味参数显著降低。口腔病理性口臭患者在4周时感官测试得分和探诊出血情况显著降低。
口服益生菌乳酸菌主要改善了生理性口臭，并且对牙周袋探诊出血也显示出有益效果。
