Perinatology Research Branch, Intramural Division, National Institute of Child Health and Human Development/NIH/DHHS, Bethesda, MD 20892, USA.
Am J Obstet Gynecol. 2010 Nov;203(5):446.e1-9. doi: 10.1016/j.ajog.2010.05.040. Epub 2010 Jul 24.
The purpose of this study was to determine the pregnancy outcome of asymptomatic patients in the second trimester with a nonmeasurable cervical length (0 mm).
This retrospective cohort study included 78 patients with singleton pregnancies and a sonographic nonmeasurable cervix that was detected at 14-28 weeks of gestation. Patients with cervical cerclage were excluded.
We found that (1) 75.3% of the patients delivered before 32 weeks of gestation; (2) the median diagnosis-to-delivery interval was 20.5 days, and the delivery rate within 7 and 14 days was 28.2% and 35.6%, respectively; and (3) patients with a nonmeasurable cervix that was diagnosed at <24 weeks of gestation had a shorter median diagnosis-to-delivery interval than patients who were diagnosed at 24-28 weeks of gestation (17.5 vs 41 days; P = .009).
Asymptomatic women with a nonmeasurable cervix in the second trimester have a median diagnosis-to-delivery interval of approximately 3 weeks. Almost 65% of these patients will not deliver within 2 weeks, yet 75% of them will deliver before 32 weeks of gestation. The earlier a nonmeasurable cervix is identified, the shorter the diagnosis-to-delivery interval.
本研究旨在探讨中孕期宫颈长度不可测（0mm）的无症状患者的妊娠结局。
本回顾性队列研究纳入了 78 例单胎妊娠且超声检查提示宫颈不可测的患者，这些患者的妊娠时间在 14-28 周之间。排除行宫颈环扎术的患者。
我们发现（1）75.3%的患者在 32 周前分娩；（2）中位诊断至分娩间隔为 20.5 天，7 天和 14 天内的分娩率分别为 28.2%和 35.6%；（3）妊娠 24 周前诊断为宫颈不可测的患者，其中位诊断至分娩间隔短于妊娠 24-28 周时诊断为宫颈不可测的患者（17.5 天比 41 天；P=0.009）。
中孕期宫颈不可测的无症状患者的中位诊断至分娩间隔约为 3 周。近 65%的患者在 2 周内不会分娩，但 75%的患者会在 32 周前分娩。宫颈不可测的诊断时间越早，诊断至分娩的间隔越短。
