Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Keck School of Medicine, University of Southern California, Los Angeles, 90033, USA.
Am J Perinatol. 2011 Apr;28(4):273-6. doi: 10.1055/s-0030-1270110. Epub 2010 Dec 6.
We sought to determine the relationship between cervical length and delivery outcome in patients who received prophylactic cervical cerclage. We performed a retrospective cohort study of patients with singleton gestations who underwent cerclage during calendar years 1999 to 2008. A total of 78 patients were included in the study. Multiple clinical characteristics and their relationships to delivery outcome were analyzed using multivariable logistic regression analysis. Cervical length at the time of surgery and history of one or more prior second-trimester losses were strongly associated with delivery at or after 32 weeks gestation ( P = 0.005 and P = 0.01, respectively). In fact, a cervical length greater than 2 cm at the time of surgery was associated with delivery at 32 weeks or greater (odds ratio 5.74, 95% confidence interval 1.78 to 18.5; P = 0.003). Cervical length was associated with the delivery outcome of patients with prophylactic cerclage and may be helpful in selection of surgical candidates.
我们旨在确定接受预防性宫颈环扎术的患者的宫颈长度与分娩结局之间的关系。我们对 1999 年至 2008 年期间接受环扎术的单胎妊娠患者进行了回顾性队列研究。共有 78 例患者纳入本研究。使用多变量逻辑回归分析了多种临床特征及其与分娩结局的关系。手术时的宫颈长度和一次或多次妊娠中期流产史与 32 周或以上分娩密切相关(P=0.005 和 P=0.01)。事实上,手术时宫颈长度大于 2cm 与 32 周或以上分娩相关(优势比 5.74,95%置信区间 1.78 至 18.5;P=0.003)。宫颈长度与预防性环扎术患者的分娩结局相关,可能有助于选择手术候选者。