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Quest for the artificial pancreas: combining technology with treatment.人工胰腺的探索:技术与治疗相结合
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本文引用的文献

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Real-Time hypoglycemia prediction suite using continuous glucose monitoring: a safety net for the artificial pancreas.实时低血糖预测套件结合连续血糖监测:人工胰腺的安全网。
Diabetes Care. 2010 Jun;33(6):1249-54. doi: 10.2337/dc09-1487.
2
Experimental evaluation of a recursive model identification technique for type 1 diabetes.1型糖尿病递归模型识别技术的实验评估
J Diabetes Sci Technol. 2009 Sep 1;3(5):1192-202. doi: 10.1177/193229680900300526.
3
Enhanced 911/global position system wizard: a telemedicine application for the prevention of severe hypoglycemia--monitor, alert, and locate.增强型911/全球定位系统向导:一种用于预防严重低血糖的远程医疗应用程序——监测、警报和定位。
J Diabetes Sci Technol. 2009 Nov 1;3(6):1501-6. doi: 10.1177/193229680900300632.
4
Safety constraints in an artificial pancreatic beta cell: an implementation of model predictive control with insulin on board.人工胰腺β细胞中的安全约束:机载胰岛素模型预测控制的实现
J Diabetes Sci Technol. 2009 May 1;3(3):536-44. doi: 10.1177/193229680900300319.
5
Clinical update on optimal prandial insulin dosing using a refined run-to-run control algorithm.使用优化的逐次运行控制算法进行最佳餐时胰岛素剂量调整的临床进展
J Diabetes Sci Technol. 2009 May 1;3(3):487-91. doi: 10.1177/193229680900300312.
6
Modular artificial beta-cell system: a prototype for clinical research.模块化人工β细胞系统:临床研究的一个原型
J Diabetes Sci Technol. 2008 Sep;2(5):863-72. doi: 10.1177/193229680800200518.
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Closed-loop control and advisory mode evaluation of an artificial pancreatic Beta cell: use of proportional-integral-derivative equivalent model-based controllers.人工胰腺β细胞的闭环控制与咨询模式评估:基于比例积分微分等效模型的控制器的应用
J Diabetes Sci Technol. 2008 Jul;2(4):636-44. doi: 10.1177/193229680800200415.
8
Physical activity-the major unaccounted impediment to closed loop control.身体活动——闭环控制中主要未被考虑的障碍。
J Diabetes Sci Technol. 2008 Jan;2(1):169-74. doi: 10.1177/193229680800200127.
9
Telemedicine and diabetes management: current challenges and future research directions.远程医疗与糖尿病管理:当前挑战与未来研究方向
J Diabetes Sci Technol. 2008 Jan;2(1):98-104. doi: 10.1177/193229680800200114.
10
Closed-loop control of artificial pancreatic Beta -cell in type 1 diabetes mellitus using model predictive iterative learning control.闭环控制 1 型糖尿病人工胰岛β细胞的模型预测迭代学习控制。
IEEE Trans Biomed Eng. 2010 Feb;57(2):211-9. doi: 10.1109/TBME.2009.2024409. Epub 2009 Jun 12.

人工胰腺的探索:技术与治疗相结合

Quest for the artificial pancreas: combining technology with treatment.

作者信息

Harvey Rebecca A, Wang Youqing, Grosman Benyamin, Percival Matthew W, Bevier Wendy, Finan Daniel A, Zisser Howard, Seborg Dale E, Jovanovic Lois, Doyle Francis J, Dassau Eyal

机构信息

Chemical Engineering, Northeastern University, Boston, Massachusetts, USA.

出版信息

IEEE Eng Med Biol Mag. 2010 Mar-Apr;29(2):53-62. doi: 10.1109/MEMB.2009.935711.

DOI:10.1109/MEMB.2009.935711
PMID:20659841
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3823381/
Abstract

The various components of the artificial pancreas puzzle are being put into place. Features such as communication, control, modeling, and learning are being realized presently. Steps have been set in motion to carry the conceptual design through simulation to clinical implementation. The challenging pieces still to be addressed include stress and exercise; as integral parts of the ultimate goal, effort has begun to shift toward overcoming the remaining hurdles to the full artificial pancreas. The artificial pancreas is close to becoming a reality, driven by technology, and the expectation that lives will be improved.

摘要

人工胰腺难题的各个组成部分正在逐步就位。诸如通信、控制、建模和学习等功能目前正在得以实现。已经启动了相关步骤,以将概念设计从模拟推进到临床应用。仍有待解决的具有挑战性的部分包括压力和运动;作为最终目标的组成部分,人们已开始努力克服全面实现人工胰腺的剩余障碍。在技术以及改善生活的期望推动下,人工胰腺已接近成为现实。