Becker John H, Wu Stephanie C
Basic Biomedical Sciences, Dr. William M. Scholl College of Podiatric Medicine at Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA.
J Am Podiatr Med Assoc. 2010 Jul-Aug;100(4):281-90. doi: 10.7547/1000281.
Fever is an active yet nonspecific response of the body to infections and other insults that cause immune cells to release cytokines, resulting in a brain prostanoid-mediated rise in body temperature. The causes, types, clinical management, and postoperative consequences of fever are reviewed in this article. Physicians use fever as a clinical sign for diagnoses and prognoses, but "fevers of unknown origin" continue to be problematic. Fevers that arise 1 or 2 days after surgery are usually due to stress and trauma, but later postoperative fevers often have more serious causes and consequences, such as wound infection. Fever is commonly encountered by podiatric physicians and surgeons, and certain procedures with the lower extremity are more likely to eventuate in fever.
发热是身体对感染及其他损伤的一种积极但非特异性的反应，这些感染及损伤会导致免疫细胞释放细胞因子，进而引起脑内前列腺素介导的体温升高。本文对发热的病因、类型、临床处理及术后后果进行了综述。医生将发热作为诊断和预后的临床体征，但“不明原因发热”仍然是个难题。术后1或2天出现的发热通常是由应激和创伤引起的，但术后较晚出现的发热往往有更严重的病因和后果，如伤口感染。足病医生和外科医生经常会遇到发热情况，而且某些下肢手术更有可能导致发热。
