Jawa D, Singh S, Somani R, Jaidka S, Sirkar K, Jaidka R
Department of Pedodontics and Preventive Dentistry, D.J. College of Dental Sciences & Research, Niwari Road, Modinagar, Uttar Pradesh, India.
J Indian Soc Pedod Prev Dent. 2010 Apr-Jun;28(2):73-7. doi: 10.4103/0970-4388.66739.
Painless dentistry, minimal intervention and thus giving comfort, relief and solace and instill positive attitude toward dental treatments, are some of the factors justifying the specialty of pediatric dentistry. Thus, this in vitro study was undertaken to compare the efficacy of a new chemomechanical caries removal agent, Papacarie (Formula and Acao), with conventional slow-speed rotary instrument (bur). Papacarie is a new formulation and has the main active ingredient papain, an endoprotein with bactericidal, bacteriostatic and anti-inflammatory actions. Twenty extracted human molar teeth with deep dentine caries and no enamel coverage were selected for the study. After the preparation of the teeth and removal of the caries with the respective methods, they were decalcified, dehydrated and embedded in paraffin blocks for histologic studies. Serial sections of 5 mum thickness were examined for the presence of bacteria under light microscope. Though complete removal of caries was achieved significantly in both the methods, there was less marked destruction of dentinal tubules in chemomechanical caries removal method by Papacarie. Thus, Papacarie is recommended as an efficient, easy to perform, comfortable and less destructive solution for the patient seeking an alternative to the conventional method.
无痛牙科、微创干预从而带来舒适、缓解和慰藉，并培养对牙科治疗的积极态度，这些都是儿童牙科专业存在的一些合理因素。因此，本体外研究旨在比较一种新型化学机械去龋剂Papacarie（配方和作用）与传统低速旋转器械（牙钻）的疗效。Papacarie是一种新配方，其主要活性成分是木瓜蛋白酶，一种具有杀菌、抑菌和抗炎作用的内蛋白酶。本研究选取了20颗拔除的患有深龋且无釉质覆盖的人类磨牙。用相应方法对牙齿进行制备和去龋后，将其脱钙、脱水并嵌入石蜡块中进行组织学研究。在光学显微镜下检查5微米厚的连续切片中细菌的存在情况。虽然两种方法都能显著实现龋坏的完全去除，但Papacarie化学机械去龋法对牙本质小管的破坏较小。因此，对于寻求传统方法替代方案的患者，Papacarie被推荐为一种高效、易于操作、舒适且破坏性较小的解决方案。
