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四环素固定化胶原膜联合根面平整术治疗牙周袋的疗效

Therapeutic effects of combined treatment using tetracycline-immobilized collagen film and root planing in periodontal furcation pockets.

作者信息

Minabe M, Takeuchi K, Nishimura T, Hori T, Umemoto T

机构信息

Department of Periodontology, Kanagawa Dental College, Japan.

出版信息

J Clin Periodontol. 1991 May;18(5):287-90. doi: 10.1111/j.1600-051x.1991.tb00430.x.

DOI:10.1111/j.1600-051x.1991.tb00430.x
PMID:2066441
Abstract

46 upper and lower molars with furcation grade II involvement were selected from 16 patients with periodontal disease. The teeth were randomly allocated to the following groups according to treatment; (1) 4 consecutive administrations of tetracycline-immobilized cross-linked collagen film (TC film) at intervals of 1 week (TC group); (2) 1 root planing treatment (RP group); (3) combination treatment (TC + RP group); (4) no treatment (control group). The therapeutic effects of each treatment were compared both clinically and microbiologically. Records of plaque index, gingival index, bleeding on probing, probing depth, probing attachment level and microscopic counts were obtained at 0, 4, 6 and 8 weeks. The results showed marked decreases in probing depth and density of micro-organisms in both the RP and TC + RP groups. In particular, the TC + RP group was characterized by a decreased rate of bleeding on pocket probing and an increased probing attachment gain. The above findings demonstrated that root planning is effective in the treatment of furcation involvement and that the effects are enhanced by the local administration of TC films.

摘要

从16名牙周病患者中选取46颗根分叉病变为II度的上下磨牙。根据治疗方法将这些牙齿随机分为以下几组:(1)每隔1周连续4次给予四环素固定交联胶原膜(TC膜)(TC组);(2)1次根面平整治疗(RP组);(3)联合治疗(TC + RP组);(4)不治疗(对照组)。对每种治疗方法的临床和微生物学治疗效果进行比较。在0、4、6和8周时记录菌斑指数、牙龈指数、探诊出血、探诊深度、探诊附着水平和微生物显微镜计数。结果显示,RP组和TC + RP组的探诊深度和微生物密度均显著降低。特别是,TC + RP组的特点是袋内探诊出血率降低,探诊附着增加。上述结果表明,根面平整对根分叉病变治疗有效,且局部应用TC膜可增强其疗效。

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引用本文的文献

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J Indian Soc Periodontol. 2016 Nov-Dec;20(6):608-613. doi: 10.4103/jisp.jisp_52_17.
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Evaluation of commercially available biodegradable tetracycline fiber therapy in chronic periodontitis.慢性牙周炎中市售可生物降解四环素纤维疗法的评估
J Indian Soc Periodontol. 2011 Apr;15(2):130-4. doi: 10.4103/0972-124X.84381.
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Evaluation of two local drug delivery systems as adjuncts to mechanotherapy as compared to mechanotherapy alone in management of chronic periodontitis: A clinical, microbiological, and molecular study.
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J Indian Soc Periodontol. 2009 Sep;13(3):126-32. doi: 10.4103/0972-124X.60224.