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宫颈和阴道类风湿性肉芽肿:具有挑战性的诊断和治疗。

Rheumatoid granuloma of the cervix and vagina: a challenging diagnosis and treatment.

机构信息

From the Departments of Obstetrics and Gynecology, Internal Medicine, and Pathology and Laboratory Medicine, American University of Beirut Medical Center, Beirut, Lebanon.

出版信息

Obstet Gynecol. 2010 Aug;116 Suppl 2:501-503. doi: 10.1097/AOG.0b013e3181d992d0.

DOI:10.1097/AOG.0b013e3181d992d0
PMID:20664433
Abstract

BACKGROUND

Granulomas of the female genital tract are rare and usually occur after operative procedures.

CASE

A patient with rheumatoid arthritis presented with vaginal discharge and bleeding with ulcerative, red, friable lesions of the cervix, which extended to the bladder floor and the right upper vaginal wall. Cervical biopsy was highly suggestive of rheumatoid nodules. This prompted revision of the diagnosis of tuberculosis, which was suspected several months earlier when pulmonary and renal lesions were noted. The cervico-vaginal lesions did not respond to local steroid treatment and improved when the systemic steroid dose was increased; however, they recurred on tapering the dose.

CONCLUSION

Rheumatoid nodules can occur in the genital tract, which poses diagnostic and treatment challenges.

摘要

背景

女性生殖道的肉芽肿很少见,通常发生在手术后。

病例

一名类风湿关节炎患者出现阴道分泌物和出血,宫颈有溃疡性、红色、易碎的病变,延伸至膀胱底部和右侧阴道上部。宫颈活检高度提示类风湿结节。这促使重新诊断为结核病,几个月前肺部和肾脏病变时就怀疑是结核病。宫颈-阴道病变对局部类固醇治疗无反应,当全身类固醇剂量增加时会改善;然而,当剂量减少时,它们又复发了。

结论

类风湿结节可发生在生殖道,这给诊断和治疗带来挑战。

相似文献

1
Rheumatoid granuloma of the cervix and vagina: a challenging diagnosis and treatment.宫颈和阴道类风湿性肉芽肿:具有挑战性的诊断和治疗。
Obstet Gynecol. 2010 Aug;116 Suppl 2:501-503. doi: 10.1097/AOG.0b013e3181d992d0.
2
[Epidemiologic study of cervico-vaginal pathology in IUD users].
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Adverse effects of pregnancy on multifocal eosinophilic granuloma.
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[Vulvo-cervico-vaginal infections caused by common (non-herpetic) germs].
Rev Fr Gynecol Obstet. 1989 Mar 25;84(3 Pt 2):257-9; discussion 265-7.
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[Differential diagnostic possibilities based on algorithms from histological study in cervical and vaginal diseases].
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Benign melanosis of the vagina and cervix.阴道和宫颈良性黑变病。
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引用本文的文献

1
Simultaneous occurrence of accelerated nodulosis in lungs, liver, and kidneys, and acute exacerbation of interstitial pneumonia in a patient with rheumatoid arthritis: an autopsy case report.类风湿关节炎患者肺部、肝脏和肾脏同时发生结节性增生病,间质性肺炎急性加重:尸检病例报告。
BMC Pulm Med. 2022 Jan 5;22(1):10. doi: 10.1186/s12890-021-01806-x.
2
Genitourinary tuberculosis: an atypical clinical presentation.泌尿生殖系统结核:一种非典型的临床表现。
Case Rep Obstet Gynecol. 2012;2012:727146. doi: 10.1155/2012/727146. Epub 2012 Dec 18.