From the Departments of Obstetrics and Gynecology, Internal Medicine, and Pathology and Laboratory Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Obstet Gynecol. 2010 Aug;116 Suppl 2:501-503. doi: 10.1097/AOG.0b013e3181d992d0.
Granulomas of the female genital tract are rare and usually occur after operative procedures.
A patient with rheumatoid arthritis presented with vaginal discharge and bleeding with ulcerative, red, friable lesions of the cervix, which extended to the bladder floor and the right upper vaginal wall. Cervical biopsy was highly suggestive of rheumatoid nodules. This prompted revision of the diagnosis of tuberculosis, which was suspected several months earlier when pulmonary and renal lesions were noted. The cervico-vaginal lesions did not respond to local steroid treatment and improved when the systemic steroid dose was increased; however, they recurred on tapering the dose.
Rheumatoid nodules can occur in the genital tract, which poses diagnostic and treatment challenges.
女性生殖道的肉芽肿很少见,通常发生在手术后。
一名类风湿关节炎患者出现阴道分泌物和出血,宫颈有溃疡性、红色、易碎的病变,延伸至膀胱底部和右侧阴道上部。宫颈活检高度提示类风湿结节。这促使重新诊断为结核病,几个月前肺部和肾脏病变时就怀疑是结核病。宫颈-阴道病变对局部类固醇治疗无反应,当全身类固醇剂量增加时会改善;然而,当剂量减少时,它们又复发了。
类风湿结节可发生在生殖道,这给诊断和治疗带来挑战。