Oxford University Centre for Clinical Magnetic Resonance Research, MRS Unit, John Radcliffe Hospital, Oxford, UK.
Magn Reson Med. 2010 Aug;64(2):610-5. doi: 10.1002/mrm.22323.
A "half-pulse" slice selection approach is used in the ultrashort echo time pulse sequence and is required to give minimal transverse relaxation in a two-dimensional acquisition. This method splits the normal excitation radiofrequency pulse in half and acquires a pair of images, each using one of these half-pulses. These half-pulses are used without a refocusing gradient since summing the pair of images yields images with accurate slice selection. When the radiofrequency pulse duration is similar to the sample T(2), characteristics such as the effective echo time and choice of radiofrequency pulse require careful evaluation as some of the approximations in conventional slice selection do not apply. We derive a theory that includes relaxation during excitation using Pauly's excitation k-space formalism. Further, this theory is tested on phantoms with a range of values of T(2) demonstrating the effect on the slice profile. We conclude that relaxation during excitation is significant and should be included in our estimate of the T(2) weighting of the sequence. In general, the T(2) weighting should be measured from the time of the centroid of the excitation pulse.
在超短回波时间脉冲序列中使用“半脉冲”切片选择方法,这在二维采集时需要最小的横向弛豫。这种方法将正常激励射频脉冲分成两半,并采集一对图像,每幅图像使用其中一个半脉冲。由于这对图像相加后可获得具有准确切片选择的图像,因此无需聚焦梯度。当射频脉冲持续时间与样品 T(2)相似时,需要仔细评估有效回波时间和射频脉冲的选择等特性,因为传统切片选择中的一些近似不再适用。我们使用 Pauly 的激发 k 空间形式推导出了一个包括激发过程中弛豫的理论。此外,该理论在具有一系列 T(2)值的体模上进行了测试,证明了它对切片轮廓的影响。我们得出结论,激发过程中的弛豫是显著的,应该包含在我们对序列 T(2)权重的估计中。一般来说,T(2)权重应该从激励脉冲的质心时间测量。