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零回波时间 MRI:硬脉冲与扫场脉冲激发。

MRI with zero echo time: hard versus sweep pulse excitation.

机构信息

Bruker BioSpin AG, Faellanden, Switzerland.

出版信息

Magn Reson Med. 2011 Aug;66(2):379-89. doi: 10.1002/mrm.22799. Epub 2011 Mar 4.

DOI:10.1002/mrm.22799
PMID:21381099
Abstract

Zero echo time can be obtained in MRI by performing radiofrequency (RF) excitation as well as acquisition in the presence of a constant gradient applied for purely frequency-encoded, radial centre-out k-space encoding. In this approach, the spatially nonselective excitation must uniformly cover the full frequency bandwidth spanned by the readout gradient. This can be accomplished either by short, hard RF pulses or by pulses with a frequency sweep as used in the SWIFT (Sweep imaging with Fourier transform) method for improved performance at limited RF amplitudes. In this work, the two options are compared with respect to T2 sensitivity, signal-to-noise ratio (SNR), and SNR efficiency. In particular, the SNR implications of sweep excitation and of initial or periodical acquisition gaps required for transmit-receive switching are investigated. It was found by simulations and experiments that, whereas equivalent in terms of T2 sensitivity, the two techniques differ in SNR performance. With ideal, ungapped simultaneous excitation and acquisition, the sweep approach would yield higher SNR throughout due to larger feasible flip angles. However, acquisition gapping is found to take a significant SNR toll related to a reduced acquisition duty cycle, rendering hard pulse excitation superior for sufficient RF amplitude and also in the short-T2 limit.

摘要

在 MRI 中,可以通过在存在施加的恒梯度的情况下执行射频 (RF) 激发以及采集来获得零回波时间,该梯度仅用于纯频率编码的、径向中心出 k 空间编码。在这种方法中,空间非选择性激发必须均匀地覆盖由读出梯度跨越的整个频率带宽。这可以通过短而硬的 RF 脉冲或具有频率扫描的脉冲来实现,如在 SWIFT(傅里叶变换的扫频成像)方法中那样,以在有限的 RF 幅度下提高性能。在这项工作中,这两种方法在 T2 灵敏度、信噪比 (SNR) 和 SNR 效率方面进行了比较。特别是,研究了扫频激发和用于收发切换的初始或周期性采集间隙的 SNR 影响。通过模拟和实验发现,尽管在 T2 灵敏度方面等效,但这两种技术在 SNR 性能上有所不同。对于理想的、无间隙的同时激发和采集,由于更大的可行翻转角,扫频方法在整个过程中会产生更高的 SNR。然而,发现采集间隙会导致与采集占空比降低相关的显著 SNR 损失,这使得硬脉冲激发在足够的 RF 幅度下以及在短 T2 限制下具有优势。

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