ermB 介导的牛乳房炎乳链球菌对红霉素的耐药性。
ermB-mediated erythromycin resistance in Streptococcus uberis from bovine mastitis.
机构信息
Agence Française de Sécurité Sanitaire des Aliments, Unité Antibiorésistance et Virulence Bactérienne, 31 Avenue Tony Garnier, 69364 Lyon, France.
出版信息
Vet J. 2011 Sep;189(3):356-8. doi: 10.1016/j.tvjl.2010.06.021. Epub 2010 Jul 27.
The ermB gene was identified in 111 erythromycin resistant isolates of Streptococcus uberis from cases of bovine mastitis associated either with a constitutive (47/111) or an inducible (64/111) phenotype, as well as a phenotypic resistance to all macrolides tested. Resistance to lincosamides was identified in 14 other isolates of S. uberis from bovine mastitis cases and was mainly mediated by the linB gene; resistance conferred by a combination of two genes (linB-lnuD, ermB-linB) was also detected.
在与奶牛乳腺炎相关的病例中，从 111 株乳链菌（Streptococcus uberis）的红霉素耐药分离株中鉴定出 ermB 基因，这些分离株表现为组成型耐药（47/111）或诱导型耐药（64/111），同时对所有测试的大环内酯类药物均表现出耐药表型。在来自奶牛乳腺炎病例的另外 14 株乳链菌的分离株中发现了对林可酰胺类的耐药性，这主要是由 linB 基因介导的；还检测到由两个基因（linB-lnuD、ermB-linB）组合赋予的耐药性。
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