Agence Française de Sécurité Sanitaire des Aliments, Unité Antibiorésistance et Virulence Bactérienne, 31 Avenue Tony Garnier, 69364 Lyon, France.
Vet J. 2011 Sep;189(3):356-8. doi: 10.1016/j.tvjl.2010.06.021. Epub 2010 Jul 27.
The ermB gene was identified in 111 erythromycin resistant isolates of Streptococcus uberis from cases of bovine mastitis associated either with a constitutive (47/111) or an inducible (64/111) phenotype, as well as a phenotypic resistance to all macrolides tested. Resistance to lincosamides was identified in 14 other isolates of S. uberis from bovine mastitis cases and was mainly mediated by the linB gene; resistance conferred by a combination of two genes (linB-lnuD, ermB-linB) was also detected.
在与奶牛乳腺炎相关的病例中，从 111 株乳链菌（Streptococcus uberis）的红霉素耐药分离株中鉴定出 ermB 基因，这些分离株表现为组成型耐药（47/111）或诱导型耐药（64/111），同时对所有测试的大环内酯类药物均表现出耐药表型。在来自奶牛乳腺炎病例的另外 14 株乳链菌的分离株中发现了对林可酰胺类的耐药性，这主要是由 linB 基因介导的；还检测到由两个基因（linB-lnuD、ermB-linB）组合赋予的耐药性。
