Tatsch K, Schroettle W, Kirsch C M
Department of Radiology, Klinikum Grosshadern, University of Munich, Germany.
J Nucl Med. 1991 Jul;32(7):1365-70.
Esophageal motility was evaluated from the analysis of six consecutive swallows. A sum image was generated comprising the representative information of an entire study. Calculation of emptying rates and characterization of the bolus behavior was performed from the sum image and the single swallow data. In 86 patients investigated, liquid and solid-phase studies showed a remarkable variation of single swallow data in normals (relative variation coefficient for liquid: 10%, solid: 14%), which were even higher (p less than 0.001) in patients with disorders (liquid: 31%, solid: 25%). As sum images compensate for this intra-individual variation, false-positive (liquid: 16%, solid: 25%) or negative single swallow findings (liquid: 36%, solid: 27%) are reduced. Qualitative analysis of condensed sum images provided characteristic image patterns representing different pathophysiologic aspects. Since the method introduced better discriminates between normal and pathologic function, it may enhance diagnostic accuracy.
通过对连续六次吞咽进行分析来评估食管动力。生成一幅汇总图像，其中包含整个研究的代表性信息。根据汇总图像和单次吞咽数据计算排空率并描述食团行为特征。在86例接受调查的患者中，液体和固体相研究显示，正常个体的单次吞咽数据存在显著差异（液体的相对变异系数为10%，固体为14%），而在疾病患者中差异更大（p<0.001）（液体：31%，固体：25%）。由于汇总图像可补偿个体内的这种差异，假阳性（液体：16%，固体：25%）或单次吞咽检查的阴性结果（液体：36%，固体：27%）会减少。对浓缩汇总图像的定性分析提供了代表不同病理生理方面的特征性图像模式。由于所介绍的方法能更好地区分正常和病理功能，它可能会提高诊断准确性。
