Unit of Public Health, Epidemiology and Biostatistics, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
Am J Epidemiol. 2010 Sep 1;172(5):501-16. doi: 10.1093/aje/kwq171. Epub 2010 Jul 28.
In this systematic review, the authors aimed to assess the effectiveness of community programs for prevention of cardiovascular disease (CVD). They searched numerous electronic databases (CDSR, DARE, HTA, EED, and CENTRAL via the Cochrane Library, MEDLINE, MEDLINE In Process, EMBASE, CINAHL, PsycINFO, HMIC, and ASSIA) and relevant Web sites from January 1970 to mid-July 2008. Controlled studies of community programs for the primary prevention of CVD were included. Net changes in CVD risk factors were used to generate an overall index for net change in 10-year CVD risk. The authors identified 36 relevant community programs that took place between 1970 and 2008. These programs were multifaceted interventions employing combinations of media, screening, and counseling activities and environmental changes and were primarily evaluated using controlled before-after studies. In 7 studies, investigators reported changes in CVD/total mortality rates, and in 5 they reported net changes. In all cases, these net changes were positive but were largely nonsignificant. In 22 studies, investigators reported changes in physiologic CVD risk factors, and there was a positive trend in the calculated CVD risk score. The average net reduction in 10-year CVD risk was 0.65%. Community programs for CVD prevention appear to have generally achieved favorable changes in overall CVD risk and, with adaptation to current circumstances, deserve continued consideration as possible approaches to preventing CVD.
在这项系统评价中,作者旨在评估社区预防心血管疾病(CVD)项目的有效性。他们搜索了大量的电子数据库(CDSR、DARE、HTA、EED 和通过 Cochrane 图书馆的 CENTRAL、MEDLINE、MEDLINE In Process、EMBASE、CINAHL、PsycINFO、HMIC 和 ASSIA)和相关的网站,时间从 1970 年 1 月到 2008 年 7 月中旬。包括了社区一级预防 CVD 的项目的对照研究。使用 CVD 风险因素的净变化来生成 10 年 CVD 风险的净变化的综合指数。作者确定了 36 项相关的社区项目,这些项目发生在 1970 年至 2008 年期间。这些项目是多方面的干预措施,采用了媒体、筛查和咨询活动以及环境变化的组合,主要通过对照前后研究进行评估。在 7 项研究中,调查人员报告了 CVD/总死亡率的变化,其中 5 项报告了净变化。在所有情况下,这些净变化都是积极的,但大多不显著。在 22 项研究中,研究人员报告了生理 CVD 风险因素的变化,计算出的 CVD 风险评分呈上升趋势。10 年 CVD 风险的平均净降低率为 0.65%。CVD 预防社区项目似乎总体上已经取得了有利的 CVD 风险变化,并且随着对当前情况的适应,值得继续考虑作为预防 CVD 的可能方法。