中国大陆肺炎发病率和死亡率：1985-2008 年中文和英文文献的系统评价。
Pneumonia incidence and mortality in Mainland China: systematic review of Chinese and English literature, 1985-2008.
机构信息
Hubei Center for Disease Control and Prevention, Hubei, People's Republic of China.
出版信息
PLoS One. 2010 Jul 23;5(7):e11721. doi: 10.1371/journal.pone.0011721.
BACKGROUND
Pneumonia is a leading infectious disease killer worldwide, yet the burden in China is not well understood as much of the data is published in the non-English literature.
METHODOLOGY/PRINCIPAL FINDINGS: We systematically reviewed the Chinese- and English-language literature for studies with primary data on pneumonia incidence and mortality in mainland China. Between 1985 and 2008, 37 studies met the inclusion criteria. The quality of the studies was highly variable. For children <5 years, incidence ranged from 0.06-0.27 episodes per person-year and mortality ranged from 184-1,223 deaths per 100,000 population. Overall incidence and mortality were stable or decreased over the study period and were higher in rural compared to urban areas.
CONCLUSIONS/SIGNIFICANCE: Pneumonia continues to be a major public health challenge in young children in China, and estimates of pneumonia incidence and mortality vary widely. Reliable surveillance data and new prevention efforts may be needed to achieve and document additional declines, especially in areas with higher incidence and mortality such as rural settings.
背景
肺炎是全球主要的传染病致死病因，但中国的肺炎负担情况并不为人们所了解，因为大量数据都发表在非英文文献中。
方法/主要发现：我们系统性地回顾了中文和英文文献，寻找关于中国大陆地区肺炎发病率和死亡率的原始数据研究。1985 年至 2008 年期间，共有 37 项研究符合纳入标准。这些研究的质量差异很大。对于<5 岁的儿童，发病率范围为 0.06-0.27 人/年，死亡率范围为每 10 万人 184-1223 例死亡。总的来说，发病率和死亡率在研究期间保持稳定或下降，且农村地区高于城市地区。
结论/意义：肺炎仍然是中国幼儿面临的一个主要公共卫生挑战，肺炎发病率和死亡率的估计值差异很大。可能需要可靠的监测数据和新的预防措施来实现并记录进一步的下降，特别是在发病率和死亡率较高的地区，如农村地区。
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