Kikuchi Y, Shindoh C, Miki H, Taguchi O, Okabe S, Chohan T, Hida W, Inoue H, Takishima T
First Department of Internal Medicine, Tohoku University School of Medicine, Sendai, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1991 Mar;29(3):293-6.
It was found that functional residual capacity (FRC) invariably decreased during inspiratory elastic loaded breathing and that its magnitude increased progressively with an increase in the intensity of the load. This response could not be explained by chemoreflexes nor neural reflexes. Because the sensation of dyspnea decreased at lowered FRC (FRC-0.5 liter) than that at FRC during elastic loading, we speculate that FRC decreased behaviorally during elastic loading to reduce the sensation of dyspnea. We found that the respiratory muscle became fatigued more easily at FRC than at lowered FRC during elastic loading. We therefore conclude that the decrease in FRC may be one of the compensatory mechanisms during elastic loaded breathing.
研究发现,在吸气弹性负荷呼吸过程中,功能残气量(FRC)始终会降低,并且其降低幅度会随着负荷强度的增加而逐渐增大。这种反应无法用化学反射或神经反射来解释。由于在弹性负荷期间,功能残气量降低0.5升时的呼吸困难感比功能残气量正常时要小,因此我们推测在弹性负荷期间,功能残气量会通过行为调节而降低,以减轻呼吸困难感。我们还发现,在弹性负荷期间,呼吸肌在功能残气量正常时比在功能残气量降低时更容易疲劳。因此,我们得出结论,功能残气量的降低可能是弹性负荷呼吸期间的一种代偿机制。