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自然式门诊环境下儿童和青少年精神病治疗的效果。

The effectiveness of child and adolescent psychiatric treatments in a naturalistic outpatient setting.

机构信息

Department of Child and Adolescent Psychiatry, University Hospital Giessen and Marburg, Campus Marburg, Hans-Sachs-Strasse 4-6, 35039 Marburg, Germany.

出版信息

World Psychiatry. 2010 Jun;9(2):111-7. doi: 10.1002/j.2051-5545.2010.tb00288.x.

Abstract

Data concerning the effectiveness of naturalistic treatments (treatment-as-usual) in child and adolescent psychiatric (CAP) services are scarce. The purpose of this prospective observational study was to examine the effectiveness of CAP treatments in a naturalistic outpatient setting. Three hundred six patients (attention-deficit/hyperactivity disorder, ADHD, n=94; conduct disorder, CD, n=57; anxiety disorder, AD, n=53; depressive disorder, DD, n=38; other diagnostic categories, n=64), from nine child and adolescent psychiatric practices in Germany, were evaluated. Treatment effects were compared between patients who received frequent treatment and patients who only participated in diagnostics and short interventions. Since randomization was not feasible, propensity score analysis methods were used. Regarding the total sample, no significant treatment effects were found. However, a subgroup analysis of the four most frequent disorders (ADHD, CD, AD, DD) showed small to moderate treatment effects in patients with ADHD and AD. In CD and DD subgroups, no significant treatment effects could be found. "Real-world" CAP outpatient treatment seems to produce significant effects for ADHD and AD, but not for CD and DD. Compared to efficacy studies, our results show that naturalistic treatment might be better than expected.

摘要

关于儿童和青少年精神病学(CAP)服务中自然疗法(常规治疗)效果的数据很少。本前瞻性观察研究的目的是在自然的门诊环境中检查 CAP 治疗的效果。来自德国九家儿童和青少年精神病学诊所的 306 名患者(注意力缺陷/多动障碍,ADHD,n=94;品行障碍,CD,n=57;焦虑障碍,AD,n=53;抑郁障碍,DD,n=38;其他诊断类别,n=64)接受了评估。在接受频繁治疗的患者和仅接受诊断和短期干预的患者之间比较了治疗效果。由于随机化不可行,因此使用了倾向评分分析方法。对于总样本,未发现显著的治疗效果。但是,对四种最常见疾病(ADHD、CD、AD、DD)的亚组分析显示,ADHD 和 AD 患者的治疗效果较小到中等。在 CD 和 DD 亚组中,未发现显著的治疗效果。“真实世界”的 CAP 门诊治疗似乎对 ADHD 和 AD 产生了显著效果,但对 CD 和 DD 没有效果。与疗效研究相比,我们的结果表明,自然疗法可能比预期的要好。

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