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应用 IntraLase FS60 飞秒激光行 120μm 和 90μm 准分子激光角膜原位磨镶术的前瞻性、对侧对照研究。

Prospective, contralateral comparison of 120-μm and 90-μm LASIK flaps using the IntraLase FS60 femtosecond laser.

机构信息

University of Utah, Department of Ophthalmology and Visual Sciences, Salt Lake City, Utah, USA.

出版信息

J Refract Surg. 2011 Apr;27(4):251-9. doi: 10.3928/1081597X-20100624-01. Epub 2010 Jul 1.

Abstract

PURPOSE

To compare differences in visual acuity, contrast sensitivity, higher order ocular aberrations, quality of life, and patient-reported outcomes at 3 and 6 months postoperatively in eyes with stable myopia undergoing thin-flap (intended flap thicknesses of 120 or 90 μm) LASIK using the VISX Star S4 CustomVue excimer laser (VISX Inc), with flaps created by the IntraLase FS60 femtosecond laser (Abbott Medical Optics).

METHODS

In this prospective study, thin-flap LASIK was performed contralaterally on 94 eyes: 47 eyes with 120-μm intended flap thickness and 47 eyes with 90-μm intended flap thickness. Primary outcome measures were uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), contrast sensitivity, and higher order aberrations.

RESULTS

At 6 months, mean values for UDVA (logMAR) were -0.064±0.077 and -0.051±0.070 in the 120-μm and 90-μm groups, respectively (n=40, P=.431). Visual acuity of 20/20 was achieved in 98% of eyes with 120-μm flaps and 95% of eyes with 90-μm flaps, whereas 20/15 vision was achieved in 50% of eyes with 120-μm flaps and 45% of eyes with 90-μm flaps (P≥.454). Both groups had significant increases in total higher order aberrations (P≤.003). Significant differences were not found between groups in contrast sensitivity (P≥.258), CDVA (P≥.726), total higher order aberrations (P≥.477), or patient-reported outcomes (P≥.132). Patients in both groups reported increased quality of life postoperatively (P≤.002).

CONCLUSIONS

Under well-controlled surgical conditions, thin-flap LASIK achieved similar results in visual acuity, contrast sensitivity, and low induction of higher order aberrations in eyes with intended flap thicknesses of either 120 or 90 μm.

摘要

目的

比较稳定性近视患者接受薄瓣(预设瓣厚度为 120 或 90μm)LASIK 手术后 3 个月和 6 个月时的视力、对比敏感度、高阶像差、生活质量和患者报告的结果,使用 VISX Star S4 CustomVue 准分子激光(VISX Inc)进行手术,使用 IntraLase FS60 飞秒激光(Abbott Medical Optics)制作瓣。

方法

在这项前瞻性研究中,对 94 只眼的对侧眼分别进行薄瓣 LASIK 手术:47 只眼预设瓣厚度为 120μm,47 只眼预设瓣厚度为 90μm。主要观察指标为未矫正远视力(UDVA)、矫正远视力(CDVA)、对比敏感度和高阶像差。

结果

6 个月时,120μm 组和 90μm 组的平均 UDVA(logMAR)分别为-0.064±0.077 和-0.051±0.070(n=40,P=.431)。120μm 组 98%的眼和 90μm 组 95%的眼获得 20/20 的视力,而 120μm 组 50%的眼和 90μm 组 45%的眼获得 20/15 的视力(P≥.454)。两组的总高阶像差均显著增加(P≤.003)。两组间对比敏感度(P≥.258)、CDVA(P≥.726)、总高阶像差(P≥.477)或患者报告的结果(P≥.132)无显著差异。两组患者术后生活质量均显著提高(P≤.002)。

结论

在严格控制的手术条件下,预设瓣厚度为 120μm 或 90μm 的薄瓣 LASIK 术后视力、对比敏感度和低阶像差诱导量相似。

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