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飞秒激光辅助白内障手术对干眼的影响。

Effects of femtosecond laser-assisted cataract surgery on dry eye.

作者信息

Shao Dewang, Zhu Xiaoquan, Sun Wei, Cheng Peng, Chen Wei, Wang Hua

机构信息

Department of Ophthalmology, Air Force Aviation Medicine Research Institute Affiliation Hospital, Beijing 100089, P.R. China.

Department of Ophthalmology, Air Force General Hospital, Beijing 100089, P.R. China.

出版信息

Exp Ther Med. 2018 Dec;16(6):5073-5078. doi: 10.3892/etm.2018.6862. Epub 2018 Oct 15.

Abstract

The aim of this study was to investigate the effect of femtosecond laser-assisted cataract surgery (FLACS) on tear film and ocular surface function. Patients with age-related cataract who underwent phacoemulsification (phaco) in Air Force Aviation Medicine Research Institute Affiliation Hospital from January 2016 to December 2016 were randomly divided into two groups. Patients in experimental group (n=123, 150 eyes) received FLACS, while patients in phaco group (n=110, 150 eyes) underwent conventional coaxial micro-incision phaco and were implanted with foldable intraocular lens (IOL). Our results showed that there were no statistically significant differences in general conditions between the two groups. Ocular surface disease index (OSDI) and corneal fluorescein staining (CFS) scores of patients in both groups after operation were significantly increased compared with those before operation, but breakup time (BUT) and Schirmer's I test scores decreased significantly at 1 week after operation compared with those before operation and basically returned to preoperative baseline levels at 3 months after operation. CFS scores and OSDI in the FLACS group at 1 day and 1 week after operation were increased more significantly than those in the phaco group, but there were no statistically significant differences at 3 months after operation. The above results showed that the effect on ocular surface function in the FLACS group after operation was greater than that in the phaco group, and the dry eye symptoms in the FLACS group were more obvious after operation. Both FLACS and conventional phaco have certain effects on the ocular surface function of patients, and there are statistically significant differences only in the early stage. FLACS has greater effects on CFS and dry eye symptoms.

摘要

本研究的目的是探讨飞秒激光辅助白内障手术(FLACS)对泪膜和眼表功能的影响。2016年1月至2016年12月在空军航空医学研究所附属医院接受超声乳化白内障吸除术(phaco)的年龄相关性白内障患者被随机分为两组。实验组患者(n = 123,150眼)接受FLACS,而phaco组患者(n = 110,150眼)接受传统同轴微切口phaco并植入可折叠人工晶状体(IOL)。我们的结果显示两组患者的一般情况无统计学显著差异。两组患者术后的眼表疾病指数(OSDI)和角膜荧光素染色(CFS)评分均较术前显著升高,但术后1周的泪膜破裂时间(BUT)和泪液分泌试验I(Schirmer's I)评分较术前显著降低,术后3个月基本恢复至术前基线水平。FLACS组术后1天和1周时的CFS评分和OSDI升高幅度比phaco组更显著,但术后3个月时无统计学显著差异。上述结果表明,FLACS组术后对眼表功能的影响大于phaco组,且FLACS组术后干眼症状更明显。FLACS和传统phaco对患者的眼表功能均有一定影响,仅在早期存在统计学显著差异。FLACS对CFS和干眼症状的影响更大。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/214e/6257160/0e149404a8d8/etm-16-06-5073-g00.jpg

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