Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, Salt Lake City, Utah 84132, USA.
J Cataract Refract Surg. 2010 Aug;36(8):1336-43. doi: 10.1016/j.jcrs.2010.02.012.
To compare visual outcomes between wavefront-guided photorefractive keratectomy (PRK) and wavefront-guided laser in situ keratomileusis (LASIK).
Academic center, Salt Lake City, Utah, USA.
In this randomized prospective study, myopic eyes were treated with wavefront-guided PRK and or wavefront-guided LASIK using a Visx Star S4 CustomVue platform with iris registration. Primary outcome measures were uncorrected (UDVA) and corrected (CDVA) distance visual acuities and manifest refraction. Secondary outcome measures were higher-order aberrations (HOAs) and contrast sensitivity.
The PRK group comprised 101 eyes and the LASIK group, 102 eyes. At 6 months, the mean UDVA was -0.03 logMAR +/- 0.10 [SD] (20/19) and 0.07 +/- 0.09 logMAR (20/24), respectively (P = .544). In both groups, 75% eyes achieved a UDVA of 20/20 or better (P = .923); 77% of eyes in the PRK group and 88% in the LASIK group were within +/-0.50 diopter of emmetropia (P = .760). There was no statistically significant difference between groups in contrast sensitivity at 3, 6, 12, or 18 cycles per degree. The mean postoperative HOA root mean square was 0.45 +/- 0.13 mum in the PRK group and 0.59 +/- 0.22 mum in the LASIK group (P = .012), representing an increase factor of 1.22 and 1.74, respectively.
Wavefront-guided PRK and wavefront-guided LASIK had similar efficacy, predictability, safety, and contrast sensitivity; however, wavefront-guided PRK induced statistically fewer HOAs than wavefront-guided LASIK at 6 months.
No author has a financial or proprietary interest in any material or method mentioned.
比较波前引导的准分子激光角膜切削术（PRK）和波前引导的激光原位角膜磨镶术（LASIK）的视力结果。
美国犹他州盐湖城的学术中心。
在这项随机前瞻性研究中，使用带有虹膜注册的 Visx Star S4 CustomVue 平台对近视眼进行波前引导的 PRK 和/或波前引导的 LASIK 治疗。主要观察指标是未矫正（UDVA）和矫正（CDVA）远视力和角膜曲率。次要观察指标是高阶像差（HOAs）和对比敏感度。
PRK 组包括 101 只眼，LASIK 组包括 102 只眼。6 个月时，平均 UDVA 分别为-0.03 logMAR +/- 0.10 [SD]（20/19）和 0.07 +/- 0.09 logMAR（20/24）（P =.544）。在两组中，75%的眼获得了 20/20 或更好的 UDVA（P =.923）；PRK 组的 77%和 LASIK 组的 88%的眼在 +/-0.50 屈光度的近视范围内（P =.760）。在 3、6、12 或 18 周/度的对比敏感度方面，两组之间没有统计学上的显著差异。PRK 组的平均术后 HOAs 均方根为 0.45 +/- 0.13 mum，LASIK 组为 0.59 +/- 0.22 mum（P =.012），分别代表 1.22 和 1.74 的增加因子。
波前引导的 PRK 和波前引导的 LASIK 具有相似的疗效、可预测性、安全性和对比敏感度；然而，在 6 个月时，波前引导的 PRK 诱导的 HOAs 统计学上比波前引导的 LASIK 少。
没有作者对任何材料或方法有财务或专有利益。
