采用 MAL-PDT 的脉冲染料激光治疗顽固性病毒性疣。
Treatment of recalcitrant viral warts with pulsed dye laser MAL-PDT.
机构信息
Dermatology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain.
出版信息
J Dermatolog Treat. 2011 Aug;22(4):226-8. doi: 10.3109/09546631003681078. Epub 2010 Aug 1.
BACKGROUND
Photodynamic therapy (PDT) has been explored for the treatment of recalcitrant viral warts (VW) with good results in recent publications.
METHODS
We carried out a descriptive and observational study in 19 patients with recalcitrant VW. Methyl aminolaevulinic acid (MAL) was occluded for 3 hours and pulsed dye laser (PDL) was used as the light source. VW were treated weekly until they were clear or for a maximum of six sessions.
RESULTS
A total of 53% of the VW cleared, and 26% of the patients demonstrated complete clearance of all their VW. The treatment was well tolerated and no adverse events were recorded.
CONCLUSIONS
PDL-PDT is an effective and well-tolerated treatment option for patients with recalcitrant VW. Though only half of patients show any improvement, responders are likely to show complete clearance of their warts.
背景
光动力疗法（PDT）已被探索用于治疗顽固性病毒性疣（VW），最近的出版物中有很好的效果。
方法
我们对 19 例顽固性 VW 患者进行了描述性和观察性研究。甲氨基酮戊酸（MAL）被封闭 3 小时，脉冲染料激光（PDL）用作光源。VW 每周治疗一次，直到清除或最多治疗 6 次。
结果
共有 53%的 VW 清除，26%的患者 VW 完全清除。治疗耐受性良好，无不良反应记录。
结论
PDL-PDT 是治疗顽固性 VW 的有效且耐受性良好的治疗选择。尽管只有一半的患者有任何改善，但反应者很可能会完全清除他们的疣。
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