Hepatitis Virus Diversity Research Programme, Department of Internal Medicine, University of the Witwatersrand, 7 York Road, Parktown, 2193 Johannesburg, South Africa.
Vaccine. 2010 Sep 7;28(39):6408-10. doi: 10.1016/j.vaccine.2010.07.042. Epub 2010 Jul 29.
Despite the recommendation of the World Health Organization (WHO) to provide the first hepatitis B vaccine dose at birth (within 24h), there are epidemiological, economic and logistical reasons why this may not be the best approach for home births in Africa. The WHO policy presupposes that the epidemiology of hepatitis B infection in Africa is similar to the rest of the world and that the organizational, infrastructural and financial support is adequate. While babies born in health facilities may be relatively easy to immunize at birth, health systems and infrastructures in many resource-poor countries in Africa would be severely challenged, if required to reach home deliveries within 24h of birth.
尽管世界卫生组织(WHO)建议在婴儿出生时(24 小时内)接种第一剂乙肝疫苗,但在非洲,由于流行病学、经济和后勤方面的原因,这可能不是家庭分娩的最佳方法。世卫组织的政策假设非洲的乙型肝炎感染流行病学与世界其他地区相似,并且组织、基础设施和财政支持充足。虽然在卫生机构出生的婴儿在出生时相对容易进行免疫接种,但如果要求在出生后 24 小时内为在家分娩的婴儿进行免疫接种,许多非洲资源贫乏国家的卫生系统和基础设施将面临严峻挑战。