乙型肝炎病毒流行病学
Hepatitis B virus epidemiology.
作者信息
MacLachlan Jennifer H, Cowie Benjamin C
机构信息
Epidemiology Unit, Victorian Infectious Diseases Reference Laboratory, Doherty Institute, Melbourne, Victoria 3000, Australia Department of Medicine, University of Melbourne, Melbourne, Victoria 3050, Australia.
Epidemiology Unit, Victorian Infectious Diseases Reference Laboratory, Doherty Institute, Melbourne, Victoria 3000, Australia Department of Medicine, University of Melbourne, Melbourne, Victoria 3050, Australia Victorian Infectious Diseases Service, Royal Melbourne Hospital, Melbourne, Victoria 3050, Australia.
出版信息
Cold Spring Harb Perspect Med. 2015 May 1;5(5):a021410. doi: 10.1101/cshperspect.a021410.
The epidemiology of hepatitis B virus (HBV) infection is geographically diverse, with population prevalence, age and mode of acquisition, and likelihood of progression to chronic infection mutually interdependent. The burden of chronic HBV infection is increasingly being recognized, with cirrhosis and liver cancer attributable to HBV continuing to increase. The outcomes of chronic HBV infection are affected by a range of factors, including viral genotype, the presence of coinfections with other blood-borne viruses, and the impact of other causes of liver disease. The increased recognition of HBV infection as a leading cause of death globally has resulted in the development of new structures and policies at the international level; immediate attention to implementing these strategies is now required.
乙型肝炎病毒（HBV）感染的流行病学在地域上具有多样性，人群患病率、感染年龄和感染方式以及进展为慢性感染的可能性相互依存。慢性HBV感染的负担日益受到重视，由HBV导致的肝硬化和肝癌病例持续增加。慢性HBV感染的结果受一系列因素影响，包括病毒基因型、与其他血源病毒合并感染的情况以及其他肝病病因的影响。全球范围内对HBV感染作为主要死因的认识不断提高，促使国际层面制定了新的架构和政策；现在需要立即关注这些策略的实施。
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