Suppr超能文献

[摩洛哥年轻患者的乳腺癌]

[Breast cancer in young patient in Morrocco].

作者信息

Boufettal H, Noun M, Samouh N

机构信息

Service de gynécologie-obstétrique C, CHU Ibn Rochd de Casablanca, 1, rue des Hôpitaux-ex Banaflous, 20360 Casablanca, Maroc.

出版信息

Cancer Radiother. 2010 Dec;14(8):698-703. doi: 10.1016/j.canrad.2010.04.007. Epub 2010 Jul 31.

Abstract

OBJECTIVE

The aim of this retrospective study is to determine the epidemiological, clinical, therapeutic aspects and prognostic factors of breast cancer in women through a comparative study of 648 patients treated for breast cancer: 165 patients are at 35 years of age or less (G 1), 286 patients are more than 35 years old and non menopausal (G 2).

PATIENT AND METHOD

We have collected, for each group, the epidemioclinical data. Nonmetastatic and operable cancer was treated by surgery (conservative or radical) followed by an adjuvant treatment (chemotherapy, radiotherapy, hormomotherapy) that was indicated according to prognosis factors. Locally advanced forms or metastatic at the moment of diagnosis were treated firstly by chemotherapy.

RESULTS

T2N1 forms with lymph node involvement, high grade (SBR II, III) and negative hormonal receptors (HR-) were predominant. There was no difference between the two groups of women concerning risk factors or clinical criterias, except for the mammography that was more sensible in the second group.

CONCLUSION

The breast cancer in our young patient doesn't seem to be different from the older ones either in clinical presentation or evolution. The conclusions of different authors are divergent but they are all for evoluated forms with more defavorable prognosis than in the older women.

摘要

目的

本回顾性研究旨在通过对648例乳腺癌患者的比较研究,确定女性乳腺癌的流行病学、临床、治疗方面及预后因素。其中165例患者年龄在35岁及以下(G1组),286例患者年龄超过35岁且未绝经(G2组)。

患者与方法

我们收集了每组的流行病学临床数据。非转移性且可手术的癌症通过手术(保乳手术或根治性手术)治疗,随后根据预后因素进行辅助治疗(化疗、放疗、激素治疗)。诊断时局部晚期或转移性癌症首先通过化疗治疗。

结果

伴有淋巴结受累的T2N1型、高级别(SBR II、III级)及激素受体阴性(HR-)的病例占主导。两组女性在危险因素或临床标准方面无差异,但乳腺钼靶检查在第二组中更敏感。

结论

我们年轻患者的乳腺癌在临床表现或病程方面似乎与老年患者没有差异。不同作者的结论存在分歧,但他们都认为进展期乳腺癌的预后比老年女性更差。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验